Investigation of <i>Atraphaxis virgata</i>, an Unexplored Medicinal Plant Rich in Flavonoids, as a Functional Material
Plants of the genus <i>Atraphaxis</i> have been widely used as traditional herbal medicines and are just beginning to be recognized for their pharmacological activities by scientific validation. In particular, <i>Atraphaxis virgata</i> (Regel) Krasn. has not reported even fun...
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2025-01-01
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| author | Soeun Shin Seunghee Kim Jeongho Lee Hyerim Son Jin-Hyub Paik Nadezhda Gennadievna Gemejiyeva Zhanat Zhumabekovna Karzhaubekova Taek Lee Hah Young Yoo |
| author_facet | Soeun Shin Seunghee Kim Jeongho Lee Hyerim Son Jin-Hyub Paik Nadezhda Gennadievna Gemejiyeva Zhanat Zhumabekovna Karzhaubekova Taek Lee Hah Young Yoo |
| author_sort | Soeun Shin |
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| description | Plants of the genus <i>Atraphaxis</i> have been widely used as traditional herbal medicines and are just beginning to be recognized for their pharmacological activities by scientific validation. In particular, <i>Atraphaxis virgata</i> (Regel) Krasn. has not reported even fundamental data, such as antioxidant activity and phytochemical properties, which requires investigation for its medical application. In this study, phytochemical compounds of <i>A. virgata</i> extracts were identified using high-performance liquid chromatography (HPLC) and gas chromatography–mass spectrometry (GC-MS) and their antioxidant activity was evaluated. As a result, <i>A. virgata</i> extracts were analyzed using HPLC and found to contain hesperidin 13.18 mg/g-extract, rutin 4.49 mg/g-extract, catechin 3.23 mg/g-extract, gallic acid 2.93 mg/g-extract, epicatechin-3-gallate 1.28 mg/g-extract, kaempferol 0.26 mg/g-extract, and luteolin 0.09 mg/g-extract. Furthermore, GC-MS analysis detected nine compounds (e.g., lup-20(29)-en-3-one and decane) in the extracts, which were reported to have various biological activities. The ABTS IC<sub>50</sub>, DPPH IC<sub>50</sub>, and FRAP values of <i>A. virgata</i> extracts were determined to be 126.57 ± 0.24 μg/mL, 42.17 ± 1.14 μg/mL, and 122.59 ± 8.79 mmol/L, respectively. This study is the first to report the antioxidant activity of <i>A. virgata</i>, suggesting its potential as a functional food or medicinal material. |
| format | Article |
| id | doaj-art-38dc847790744bd2b50f93fbcdbe6368 |
| institution | Kabale University |
| issn | 2311-7524 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Horticulturae |
| spelling | doaj-art-38dc847790744bd2b50f93fbcdbe63682025-01-24T13:34:40ZengMDPI AGHorticulturae2311-75242025-01-011117010.3390/horticulturae11010070Investigation of <i>Atraphaxis virgata</i>, an Unexplored Medicinal Plant Rich in Flavonoids, as a Functional MaterialSoeun Shin0Seunghee Kim1Jeongho Lee2Hyerim Son3Jin-Hyub Paik4Nadezhda Gennadievna Gemejiyeva5Zhanat Zhumabekovna Karzhaubekova6Taek Lee7Hah Young Yoo8Department of Biotechnology, Sangmyung University, Seoul 03016, Republic of KoreaDepartment of Biotechnology, Sangmyung University, Seoul 03016, Republic of KoreaDepartment of Biotechnology, Sangmyung University, Seoul 03016, Republic of KoreaDepartment of Biotechnology, Sangmyung University, Seoul 03016, Republic of KoreaInternational Biological Material Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of KoreaPlant Resource Laboratory, Institute of Botany and Phytointroduction, Almaty 050040, KazakhstanPlant Resource Laboratory, Institute of Botany and Phytointroduction, Almaty 050040, KazakhstanDepartment of Chemical Engineering, Kwangwoon University, Seoul 01897, Republic of KoreaDepartment of Biotechnology, Sangmyung University, Seoul 03016, Republic of KoreaPlants of the genus <i>Atraphaxis</i> have been widely used as traditional herbal medicines and are just beginning to be recognized for their pharmacological activities by scientific validation. In particular, <i>Atraphaxis virgata</i> (Regel) Krasn. has not reported even fundamental data, such as antioxidant activity and phytochemical properties, which requires investigation for its medical application. In this study, phytochemical compounds of <i>A. virgata</i> extracts were identified using high-performance liquid chromatography (HPLC) and gas chromatography–mass spectrometry (GC-MS) and their antioxidant activity was evaluated. As a result, <i>A. virgata</i> extracts were analyzed using HPLC and found to contain hesperidin 13.18 mg/g-extract, rutin 4.49 mg/g-extract, catechin 3.23 mg/g-extract, gallic acid 2.93 mg/g-extract, epicatechin-3-gallate 1.28 mg/g-extract, kaempferol 0.26 mg/g-extract, and luteolin 0.09 mg/g-extract. Furthermore, GC-MS analysis detected nine compounds (e.g., lup-20(29)-en-3-one and decane) in the extracts, which were reported to have various biological activities. The ABTS IC<sub>50</sub>, DPPH IC<sub>50</sub>, and FRAP values of <i>A. virgata</i> extracts were determined to be 126.57 ± 0.24 μg/mL, 42.17 ± 1.14 μg/mL, and 122.59 ± 8.79 mmol/L, respectively. This study is the first to report the antioxidant activity of <i>A. virgata</i>, suggesting its potential as a functional food or medicinal material.https://www.mdpi.com/2311-7524/11/1/70medical plant<i>Atraphaxis virgata</i>phytochemical compoundantioxidant |
| spellingShingle | Soeun Shin Seunghee Kim Jeongho Lee Hyerim Son Jin-Hyub Paik Nadezhda Gennadievna Gemejiyeva Zhanat Zhumabekovna Karzhaubekova Taek Lee Hah Young Yoo Investigation of <i>Atraphaxis virgata</i>, an Unexplored Medicinal Plant Rich in Flavonoids, as a Functional Material Horticulturae medical plant <i>Atraphaxis virgata</i> phytochemical compound antioxidant |
| title | Investigation of <i>Atraphaxis virgata</i>, an Unexplored Medicinal Plant Rich in Flavonoids, as a Functional Material |
| title_full | Investigation of <i>Atraphaxis virgata</i>, an Unexplored Medicinal Plant Rich in Flavonoids, as a Functional Material |
| title_fullStr | Investigation of <i>Atraphaxis virgata</i>, an Unexplored Medicinal Plant Rich in Flavonoids, as a Functional Material |
| title_full_unstemmed | Investigation of <i>Atraphaxis virgata</i>, an Unexplored Medicinal Plant Rich in Flavonoids, as a Functional Material |
| title_short | Investigation of <i>Atraphaxis virgata</i>, an Unexplored Medicinal Plant Rich in Flavonoids, as a Functional Material |
| title_sort | investigation of i atraphaxis virgata i an unexplored medicinal plant rich in flavonoids as a functional material |
| topic | medical plant <i>Atraphaxis virgata</i> phytochemical compound antioxidant |
| url | https://www.mdpi.com/2311-7524/11/1/70 |
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