Proteome-wide analysis of disease-associated SNPs that show allele-specific transcription factor binding.

A causative role for single nucleotide polymorphisms (SNPs) in many genetic disorders has become evident through numerous genome-wide association studies. However, identification of these common causal variants and the molecular mechanisms underlying these associations remains a major challenge. Dif...

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Bibliographic Details
Main Authors: Falk Butter, Lucy Davison, Tar Viturawong, Marion Scheibe, Michiel Vermeulen, John A Todd, Matthias Mann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-09-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002982&type=printable
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