An analytical “quality by design” approach in RP-HPLC method development and validation for reliable and rapid estimation of irinotecan in an injectable formulation
The objective of the present study was to develop a robust, simple, economical and sensitive HPLC-UV method using the “quality-by-design” approach for the estimation of irinotecan (IRI) in marketed formulations. RP-HPLC method was developed by applying Box-Behnken design with Hyper-Clone (Phenomenex...
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Main Authors: | Bhaskaran Navya Ajitkumar, Kumar Lalit, Reddy M Sreenivasa, Pai Girish K |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2021-03-01
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Series: | Acta Pharmaceutica |
Subjects: | |
Online Access: | https://doi.org/10.2478/acph-2021-0008 |
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