Serum Osteocalcin Is Associated with Inflammatory Factors in Metabolic Syndrome: A Population-Based Study in Chinese Males
Osteocalcin (OCN) was potentially associated with inflammatory factors, so we explored the metabolic role in this association in general population. Our findings suggest that OCN was positively associated with IgG while inversely associated with C3, both of which were probably mediated by obesity. M...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2015/683739 |
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| _version_ | 1832551452977922048 |
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| author | Ming Liao Lirong Huang Yan Mao Yonghua Jiang Ziting Yao Xinggu Lin Zheng Lu Chunlei Wu Xue Qin Haiying Zhang Zengnan Mo |
| author_facet | Ming Liao Lirong Huang Yan Mao Yonghua Jiang Ziting Yao Xinggu Lin Zheng Lu Chunlei Wu Xue Qin Haiying Zhang Zengnan Mo |
| author_sort | Ming Liao |
| collection | DOAJ |
| description | Osteocalcin (OCN) was potentially associated with inflammatory factors, so we explored the metabolic role in this association in general population. Our findings suggest that OCN was positively associated with IgG while inversely associated with C3, both of which were probably mediated by obesity. Moreover, serum OCN was inversely associated with hsCRP in men with impaired fasting glucose, hyperglycemia, or metabolic syndrome, while its association with IgE was significantly observed in men with a normal metabolic profile. |
| format | Article |
| id | doaj-art-38bd7f57a021495486854382b3b12926 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-38bd7f57a021495486854382b3b129262025-02-03T06:01:23ZengWileyMediators of Inflammation0962-93511466-18612015-01-01201510.1155/2015/683739683739Serum Osteocalcin Is Associated with Inflammatory Factors in Metabolic Syndrome: A Population-Based Study in Chinese MalesMing Liao0Lirong Huang1Yan Mao2Yonghua Jiang3Ziting Yao4Xinggu Lin5Zheng Lu6Chunlei Wu7Xue Qin8Haiying Zhang9Zengnan Mo10Institute of Urology and Nephrology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, ChinaCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi 530021, ChinaDepartment of Oncology, Third Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530031, ChinaCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi 530021, ChinaCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi 530021, ChinaCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi 530021, ChinaInstitute of Urology and Nephrology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, ChinaCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi 530021, ChinaCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi 530021, ChinaCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi 530021, ChinaInstitute of Urology and Nephrology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, ChinaOsteocalcin (OCN) was potentially associated with inflammatory factors, so we explored the metabolic role in this association in general population. Our findings suggest that OCN was positively associated with IgG while inversely associated with C3, both of which were probably mediated by obesity. Moreover, serum OCN was inversely associated with hsCRP in men with impaired fasting glucose, hyperglycemia, or metabolic syndrome, while its association with IgE was significantly observed in men with a normal metabolic profile.http://dx.doi.org/10.1155/2015/683739 |
| spellingShingle | Ming Liao Lirong Huang Yan Mao Yonghua Jiang Ziting Yao Xinggu Lin Zheng Lu Chunlei Wu Xue Qin Haiying Zhang Zengnan Mo Serum Osteocalcin Is Associated with Inflammatory Factors in Metabolic Syndrome: A Population-Based Study in Chinese Males Mediators of Inflammation |
| title | Serum Osteocalcin Is Associated with Inflammatory Factors in Metabolic Syndrome: A Population-Based Study in Chinese Males |
| title_full | Serum Osteocalcin Is Associated with Inflammatory Factors in Metabolic Syndrome: A Population-Based Study in Chinese Males |
| title_fullStr | Serum Osteocalcin Is Associated with Inflammatory Factors in Metabolic Syndrome: A Population-Based Study in Chinese Males |
| title_full_unstemmed | Serum Osteocalcin Is Associated with Inflammatory Factors in Metabolic Syndrome: A Population-Based Study in Chinese Males |
| title_short | Serum Osteocalcin Is Associated with Inflammatory Factors in Metabolic Syndrome: A Population-Based Study in Chinese Males |
| title_sort | serum osteocalcin is associated with inflammatory factors in metabolic syndrome a population based study in chinese males |
| url | http://dx.doi.org/10.1155/2015/683739 |
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