Potential renoprotective effects and possible underlying mechanisms of angiotensin receptor-neprilysin inhibitors in cardiorenal syndrome

Potential renoprotective effects and possible underlying mechanisms of angiotensin receptor-neprilysin inhibitors in cardiorenal syndrome

Angiotensin receptor-neprilysin inhibitors (ARNIs) represent a novel class of medications characterized by their dual action on major cardiorenal regulators, specifically the renin–angiotensin system (RAS) and the natriuretic peptide (NP) system. Sacubitril/valsartan, a pioneering ARNI, has demonstr...

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Bibliographic Details
Main Authors: Md. Moshiur Rahman, Asadur Rahman, Akira Nishiyama
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Medicine
Subjects:
ARNIs
cardiorenal syndrome
renoprotective effects
molecular mechanisms
pre-clinical evidence
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1451450/full
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