Dexmedetomidine pretreatment enhances protective effect efficacy of pericytes agaist acute lung injury in septic mice

Dexmedetomidine pretreatment enhances protective effect efficacy of pericytes agaist acute lung injury in septic mice

Objective　‍To investigate the effect and mechanism of dexmedetomidine （Dex） pretreated pericytes （Dex-PCs） on acute lung injury （ALI） in septic mice.Methods‍　‍Mouse model of sepsis-ALI was established with intraperitoneal injection of lipopolysaccharide （LPS） at a dose of 10 mg/kg. A total of 96 C57...

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Bibliographic Details
Main Authors: LUO Xi, ZHANG Zisen, YANG Ao
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2025-01-01
Series:陆军军医大学学报
Subjects:
dexmedetomidine
pericytes
sepsis
acute lung injury
pulmonary vascular barrier function
Online Access:https://aammt.tmmu.edu.cn/html/202407011.html
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