Mesh Exposure and Associated Risk Factors in Women Undergoing Transvaginal Prolapse Repair with Mesh

Objective. To determine frequency, rate, and risk factors associated with mesh exposure in women undergoing transvaginal prolapse repair with polypropylene mesh. Methods. Retrospective chart review was performed for all women who underwent Prolift Pelvic Floor Repair System (Gynecare, Somerville, N...

Full description

Saved in:
Bibliographic Details
Main Authors: Elizabeth A. Frankman, Marianna Alperin, Gary Sutkin, Leslie Meyn, Halina M. Zyczynski
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2013/926313
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832545425492541440
author Elizabeth A. Frankman
Marianna Alperin
Gary Sutkin
Leslie Meyn
Halina M. Zyczynski
author_facet Elizabeth A. Frankman
Marianna Alperin
Gary Sutkin
Leslie Meyn
Halina M. Zyczynski
author_sort Elizabeth A. Frankman
collection DOAJ
description Objective. To determine frequency, rate, and risk factors associated with mesh exposure in women undergoing transvaginal prolapse repair with polypropylene mesh. Methods. Retrospective chart review was performed for all women who underwent Prolift Pelvic Floor Repair System (Gynecare, Somerville, NJ) between September 2005 and September 2008. Multivariable logistic regression was performed to identify risk factors for mesh exposure. Results. 201 women underwent Prolift. Mesh exposure occurred in 12% (24/201). Median time to mesh exposure was 62 days (range: 10–372). When mesh was placed in the anterior compartment, the frequency of mesh exposure was higher than that when mesh was placed in the posterior compartment (8.7% versus 2.9%, P=0.04). Independent risk factors for mesh exposure were diabetes (AOR = 7.7, 95% CI 1.6–37.6; P=0.01) and surgeon (AOR = 7.3, 95% CI 1.9–28.6; P=0.004). Conclusion. Women with diabetes have a 7-fold increased risk for mesh exposure after transvaginal prolapse repair using Prolift. The variable rate of mesh exposure amongst surgeons may be related to technique. The anterior vaginal wall may be at higher risk of mesh exposure as compared to the posterior vaginal wall.
format Article
id doaj-art-38695ae77ff34ee79288d64de02dc79e
institution Kabale University
issn 1687-9589
1687-9597
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Obstetrics and Gynecology International
spelling doaj-art-38695ae77ff34ee79288d64de02dc79e2025-02-03T07:25:53ZengWileyObstetrics and Gynecology International1687-95891687-95972013-01-01201310.1155/2013/926313926313Mesh Exposure and Associated Risk Factors in Women Undergoing Transvaginal Prolapse Repair with MeshElizabeth A. Frankman0Marianna Alperin1Gary Sutkin2Leslie Meyn3Halina M. Zyczynski4Division of Urogynecology, Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital, University of Pittsburgh School of Medicine, 300 Halket Street, Pittsburgh, PA 15213, USADivision of Urogynecology, Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital, University of Pittsburgh School of Medicine, 300 Halket Street, Pittsburgh, PA 15213, USADivision of Urogynecology, Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital, University of Pittsburgh School of Medicine, 300 Halket Street, Pittsburgh, PA 15213, USAMagee-Womens Research Institute, 204 Craft Avenue, Pittsburgh, PA 15213, USADivision of Urogynecology, Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital, University of Pittsburgh School of Medicine, 300 Halket Street, Pittsburgh, PA 15213, USAObjective. To determine frequency, rate, and risk factors associated with mesh exposure in women undergoing transvaginal prolapse repair with polypropylene mesh. Methods. Retrospective chart review was performed for all women who underwent Prolift Pelvic Floor Repair System (Gynecare, Somerville, NJ) between September 2005 and September 2008. Multivariable logistic regression was performed to identify risk factors for mesh exposure. Results. 201 women underwent Prolift. Mesh exposure occurred in 12% (24/201). Median time to mesh exposure was 62 days (range: 10–372). When mesh was placed in the anterior compartment, the frequency of mesh exposure was higher than that when mesh was placed in the posterior compartment (8.7% versus 2.9%, P=0.04). Independent risk factors for mesh exposure were diabetes (AOR = 7.7, 95% CI 1.6–37.6; P=0.01) and surgeon (AOR = 7.3, 95% CI 1.9–28.6; P=0.004). Conclusion. Women with diabetes have a 7-fold increased risk for mesh exposure after transvaginal prolapse repair using Prolift. The variable rate of mesh exposure amongst surgeons may be related to technique. The anterior vaginal wall may be at higher risk of mesh exposure as compared to the posterior vaginal wall.http://dx.doi.org/10.1155/2013/926313
spellingShingle Elizabeth A. Frankman
Marianna Alperin
Gary Sutkin
Leslie Meyn
Halina M. Zyczynski
Mesh Exposure and Associated Risk Factors in Women Undergoing Transvaginal Prolapse Repair with Mesh
Obstetrics and Gynecology International
title Mesh Exposure and Associated Risk Factors in Women Undergoing Transvaginal Prolapse Repair with Mesh
title_full Mesh Exposure and Associated Risk Factors in Women Undergoing Transvaginal Prolapse Repair with Mesh
title_fullStr Mesh Exposure and Associated Risk Factors in Women Undergoing Transvaginal Prolapse Repair with Mesh
title_full_unstemmed Mesh Exposure and Associated Risk Factors in Women Undergoing Transvaginal Prolapse Repair with Mesh
title_short Mesh Exposure and Associated Risk Factors in Women Undergoing Transvaginal Prolapse Repair with Mesh
title_sort mesh exposure and associated risk factors in women undergoing transvaginal prolapse repair with mesh
url http://dx.doi.org/10.1155/2013/926313
work_keys_str_mv AT elizabethafrankman meshexposureandassociatedriskfactorsinwomenundergoingtransvaginalprolapserepairwithmesh
AT mariannaalperin meshexposureandassociatedriskfactorsinwomenundergoingtransvaginalprolapserepairwithmesh
AT garysutkin meshexposureandassociatedriskfactorsinwomenundergoingtransvaginalprolapserepairwithmesh
AT lesliemeyn meshexposureandassociatedriskfactorsinwomenundergoingtransvaginalprolapserepairwithmesh
AT halinamzyczynski meshexposureandassociatedriskfactorsinwomenundergoingtransvaginalprolapserepairwithmesh