The value of interferon therapy for COVID-19 in children

The value of interferon therapy for COVID-19 in children

The article presents a literature review, which provides data on the role of interferons in the immunopathogenesis of COVID-19 and the clinical efficacy of drugs based on recombinant interferon-alpha 2b in the treatment of children with new coronavirus infection. Shown the leading role ofinterferons...

Full description

Saved in:

Bibliographic Details
Main Authors:	L. N. Mazankova, S. G. Gorbunov, E. R. Samitova
Format:	Article
Language:	Russian
Published:	LLC "Diagnostics and Vaccines" 2021-04-01
Series:	Детские инфекции (Москва)
Subjects:	covid-19 sars-cov-2 interferon alpha 2b interferon therapy children
Online Access:	https://detinf.elpub.ru/jour/article/view/569
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Influence of interferon types on COVID-19 prevention and treatment
by: S. S. Saidov, et al.
Published: (2021-10-01)

Evaluation of the effectiveness of antiviral therapy for coronavirus infection (COVID-19) with the inclusion of recombinant interferon alpha-2b
by: A. V. Mordyk, et al.
Published: (2022-10-01)

Interferon Status and Choice of Interferons Inducers in Frequently Ill Children
by: M. S. Savenkovа, et al.
Published: (2016-06-01)

Evaluation of the effectiveness and safety of interferon alpha-2b ointment and gel for prevention of acute respiratory infections in organized groups
by: K. V. Kozlov, et al.
Published: (2024-04-01)

The Role of Anti-Interferon-α Autoantibodies in Severe COVID-19: Implications for Vaccination Prioritization
by: Xin Rong Lim, et al.
Published: (2025-07-01)

Cycloferon as a Means for Prevention, Treatment, and Control of COVID-19: Multidisciplinary and Comparative Historical Aspects
by: P. V. MAZIN, et al.
Published: (2022-09-01)

Рreventive efficacy of interferon -2b in the COVID-19 pandemic
by: Zh. B. Ponezheva, et al.
Published: (2021-06-01)

Combined forms of COVID-19 with acute respiratory viral infections in children
by: L. N. Mazankova, et al.
Published: (2022-03-01)

The use in pediatrics of recombinant interferon alfa-2b preparations in the dosage form rectal suppositories: whom? when? which ones?
by: M. S. Savenkova, et al.
Published: (2021-04-01)

SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists
by: Chun-Kit Yuen, et al.
Published: (2020-01-01)

Clinical and Epidemiological Features of COVID-19 in Children in Moscow in 2020–2022
by: E. R. Samitova
Published: (2022-11-01)

Nonproductive exposure of PBMCs to SARS‐CoV‐2 induces cell‐intrinsic innate immune responses
by: Julia Kazmierski, et al.
Published: (2022-08-01)

The use of combined interferon alpha-2b-based medicine in the complex treatment of herpetic keratitis in patients after coronavirus infection
by: A. V. Surov, et al.
Published: (2023-07-01)

FEATURES OF THE IMMUNE RESPONSE AND EFFICACY IMMUNOTHERAPY FOR ROTAVIRUS INFECTION IN CHILDREN
by: S. G. Gorbunov, et al.
Published: (2018-09-01)

Features of the course of COVID-19 in combination with respiratory mycoplasmosis in children
by: N. A. Dracheva, et al.
Published: (2022-11-01)

Interferons alpha and gamma, pidotimod, and tilorone in the treatment of acute respiratory infections in patients with allergic rhinitis: a prospective, cohort clinical and immunological study
by: O. V. Kalyuzhin, et al.
Published: (2022-07-01)

The common genetic variant rs1278960 determining expression of Interferon-lambda predicts inflammatory response in critically ill COVID-19 patients
by: Timo Mayerhöfer, et al.
Published: (2025-05-01)

Interferon alpha-induced reduction in the values of myeloid-derived suppressor cells in melanoma patients
by: Stanojević Ivan, et al.
Published: (2015-01-01)

Interferon alpha-2b addition to intravitreal bevacizumab for diabetic macular edema: a randomized controlled trial
by: Saeed Karimi, et al.
Published: (2025-04-01)

TYROSINE KINASE INHIBITORS AND INTERFERON
by: Maria Dimou, et al.
Published: (2014-01-01)

Chronic hepatitis b with type I diabetes mellitus and autoimmune thyroiditis development during interferon alpha therapy
by: Sukran Kose, et al.
Published: (2011-07-01)

The efficiency of interferon therapy for acute respiratory viral infections in young children
by: T. K. Chudakova, et al.
Published: (2020-03-01)

Mutations in SARS-CoV-2 variant nsp6 enhance type-I interferon antagonism
by: Cody J. Bills, et al.
Published: (2023-12-01)

PREVALENCE OF SIDE EFFECTS OF INTERFERON THERAPY IN CHILDREN WITH CHRONIC VIRAL HEPATITIS C
by: T. A. Skvortsova, et al.
Published: (2013-05-01)

Review of human interferons and the potential of their use in the complex therapy of a new coronavirus infection COVID-19
by: E. V. Granatov, et al.
Published: (2022-08-01)

IMMUNOPATHOGENESIS OF ACUTE RESPIRATORY INFECTIONS AND TACTICS OF RATIONAL CHOICE OF ETIOTROPIC IMMUNOMODULATORY THERAPIES IN CHILDREN
by: V. V. Malinovskaya, et al.
Published: (2015-08-01)

Clinical and epidemiological features of the course of the new coronavirus infection COVID-19 in children during periods of an increase in the incidence in Moscow in 2020-2021
by: L. N. Mazankova, et al.
Published: (2021-10-01)

Genomic profiling of interferon signaling pathway gene mutations in type 2 diabetic individuals with COVID-19
by: Tuluk Tuncay, et al.
Published: (2024-12-01)

Low level of tonic interferon signalling is associated with enhanced susceptibility to SARS-CoV-2 variants of concern in human lung organoids
by: Meaghan Flagg, et al.
Published: (2023-12-01)

Treatment of intrauterine infection of viral and bacterial etiology in newborns with drugs of recombinant interferon alfa-2b in the Republic of Kyrgyzstan
by: E. M. Alymkulova, et al.
Published: (2023-02-01)

Cytokine status indicators in children with acute respiratory viral infections after treatment with intranasal interferon-based medicine
by: O. I. Afanasyeva, et al.
Published: (2021-12-01)

Results of using interferon α-2b in combination with vitamins E and C in the treatment of urogenital infections in pregnant women
by: T. A. Ruzhentsova, et al.
Published: (2021-06-01)

Successful treatment of hairy cell leukaemia with pegylated interferon-alpha-2A
by: Kata Ferenczi, et al.
Published: (2025-05-01)

An Outbreak of a New Coronavirus Infection COVID-19 in an Educational Institution in Moscow
by: L N Mazankova, et al.
Published: (2022-03-01)

Targeting CTP synthetase 1 to restore interferon induction and impede nucleotide synthesis in SARS-CoV-2 infection
by: Youliang Rao, et al.
Published: (2025-06-01)

Etiological and immunopathogenetic aspects of multiorgan failure development in coronavirus disease (COVID-19)
by: T. V. Ashcheulova, et al.
Published: (2024-07-01)

Efficacy and safety of interferon alfa-2b in the complex therapy of patients with chronic bacterial prostatitis: a multicenter randomized clinical trial
by: Kh. S. Ibishev, et al.
Published: (2023-04-01)

A cGAMP‐Containing Hydrogel for Prolonged SARS‐CoV‐2 Receptor‐Binding Domain Subunit Vaccine Exposure Induces a Broad and Potent Humoral Response
by: Volker Böhnert, et al.
Published: (2025-01-01)

Epithelial response to IFN‐γ promotes SARS‐CoV‐2 infection
by: Julian Heuberger, et al.
Published: (2021-03-01)

Viferon Suppositoria in Therapy of Relapsing Herpesvirus Infection in Women
by: A. N. Vasilyev, et al.
Published: (2020-05-01)