Short-term outcomes of open versus laparoscopic surgery in patients with metachronous colorectal cancer
Abstract Background Few studies have assessed the safety and efficacy of laparoscopic surgery in patients with metachronous colorectal cancer (MCRC). This study aims to evaluate the safety and outcomes of laparoscopic surgery in MCRC patients who have previously undergone colorectal cancer surgery....
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BMC
2025-01-01
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| Series: | BMC Surgery |
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| Online Access: | https://doi.org/10.1186/s12893-025-02769-0 |
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| author | Jiyun Li Ruoxi Tian Hengchang Liu Haipeng Chen Zhaoxu Zheng |
| author_facet | Jiyun Li Ruoxi Tian Hengchang Liu Haipeng Chen Zhaoxu Zheng |
| author_sort | Jiyun Li |
| collection | DOAJ |
| description | Abstract Background Few studies have assessed the safety and efficacy of laparoscopic surgery in patients with metachronous colorectal cancer (MCRC). This study aims to evaluate the safety and outcomes of laparoscopic surgery in MCRC patients who have previously undergone colorectal cancer surgery. Methods We compared the short-term outcomes of open versus laparoscopic surgery in patients with MCRC between October 2007 and October 2022. Results Among the 59 MCRC patients, 25 underwent laparoscopic surgery, whereas 34 received open surgery. The proportion of patients who underwent prior open surgeries was significantly greater in the open group than in the laparoscopic group (91.2% vs. 24.0%, p < 0.001). Three patients (12.0%) in the laparoscopic group required conversion to laparotomy due to severe intra-abdominal adhesions, all of whom had a history of open surgery for colorectal cancer. Compared to the open surgery group, the laparoscopic group presented significantly less estimated blood loss (56.80 ± 115.47 vs. 136.47 ± 158.61 ml, p = 0.038), a shorter time to the first flatus (2.20 ± 0.76 vs. 3.50 ± 0.62 days, p < 0.001), a shorter time to the first stool (2.92 ± 0.64 vs. 4.32 ± 0.64 days, p < 0.001), and a shorter postoperative hospitalization duration (7.24 ± 2.42 vs. 10.79 ± 3.50 days, p < 0.001). Conclusion Laparoscopic surgery for MCRC patients is a safe and less invasive alternative to open surgery, resulting in reduced estimated blood loss, faster recovery of bowel function, and shorter postoperative hospitalization. |
| format | Article |
| id | doaj-art-3859336c18104e0f81828d524f43bae9 |
| institution | Kabale University |
| issn | 1471-2482 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj-art-3859336c18104e0f81828d524f43bae92025-01-26T12:12:37ZengBMCBMC Surgery1471-24822025-01-012511810.1186/s12893-025-02769-0Short-term outcomes of open versus laparoscopic surgery in patients with metachronous colorectal cancerJiyun Li0Ruoxi Tian1Hengchang Liu2Haipeng Chen3Zhaoxu Zheng4Department of Colorectal Surgery, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeDepartment of Colorectal Surgery, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeDepartment of Colorectal Surgery, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeDepartment of Colorectal Surgery, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeDepartment of Colorectal Surgery, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeAbstract Background Few studies have assessed the safety and efficacy of laparoscopic surgery in patients with metachronous colorectal cancer (MCRC). This study aims to evaluate the safety and outcomes of laparoscopic surgery in MCRC patients who have previously undergone colorectal cancer surgery. Methods We compared the short-term outcomes of open versus laparoscopic surgery in patients with MCRC between October 2007 and October 2022. Results Among the 59 MCRC patients, 25 underwent laparoscopic surgery, whereas 34 received open surgery. The proportion of patients who underwent prior open surgeries was significantly greater in the open group than in the laparoscopic group (91.2% vs. 24.0%, p < 0.001). Three patients (12.0%) in the laparoscopic group required conversion to laparotomy due to severe intra-abdominal adhesions, all of whom had a history of open surgery for colorectal cancer. Compared to the open surgery group, the laparoscopic group presented significantly less estimated blood loss (56.80 ± 115.47 vs. 136.47 ± 158.61 ml, p = 0.038), a shorter time to the first flatus (2.20 ± 0.76 vs. 3.50 ± 0.62 days, p < 0.001), a shorter time to the first stool (2.92 ± 0.64 vs. 4.32 ± 0.64 days, p < 0.001), and a shorter postoperative hospitalization duration (7.24 ± 2.42 vs. 10.79 ± 3.50 days, p < 0.001). Conclusion Laparoscopic surgery for MCRC patients is a safe and less invasive alternative to open surgery, resulting in reduced estimated blood loss, faster recovery of bowel function, and shorter postoperative hospitalization.https://doi.org/10.1186/s12893-025-02769-0Metachronous colorectal cancerLaparoscopic surgeryOpen surgeryShort-term outcomes |
| spellingShingle | Jiyun Li Ruoxi Tian Hengchang Liu Haipeng Chen Zhaoxu Zheng Short-term outcomes of open versus laparoscopic surgery in patients with metachronous colorectal cancer BMC Surgery Metachronous colorectal cancer Laparoscopic surgery Open surgery Short-term outcomes |
| title | Short-term outcomes of open versus laparoscopic surgery in patients with metachronous colorectal cancer |
| title_full | Short-term outcomes of open versus laparoscopic surgery in patients with metachronous colorectal cancer |
| title_fullStr | Short-term outcomes of open versus laparoscopic surgery in patients with metachronous colorectal cancer |
| title_full_unstemmed | Short-term outcomes of open versus laparoscopic surgery in patients with metachronous colorectal cancer |
| title_short | Short-term outcomes of open versus laparoscopic surgery in patients with metachronous colorectal cancer |
| title_sort | short term outcomes of open versus laparoscopic surgery in patients with metachronous colorectal cancer |
| topic | Metachronous colorectal cancer Laparoscopic surgery Open surgery Short-term outcomes |
| url | https://doi.org/10.1186/s12893-025-02769-0 |
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