Kartogenin Improves Osteogenesis of Bone Marrow Mesenchymal Stem Cells via Autophagy

Kartogenin Improves Osteogenesis of Bone Marrow Mesenchymal Stem Cells via Autophagy

Kartogenin (KGN), a novel small-molecule compound, has been considered a promising chondrogenic promoter in cartilage regeneration. However, whether KGN also participates in osteogenesis and bone regeneration remains unclear. This research was designed to explore the roles of KGN on osteogenic diffe...

Full description

Saved in:

Bibliographic Details
Main Authors:	Huichun Yan, Tingting Yu, Jing Li, Ting Zhang, Qian Li, Yanheng Zhou, Dawei Liu
Format:	Article
Language:	English
Published:	Wiley 2022-01-01
Series:	Stem Cells International
Online Access:	http://dx.doi.org/10.1155/2022/1278921
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

The m6A Reader YTHDF1 Accelerates the Osteogenesis of Bone Marrow Mesenchymal Stem Cells Partly via Activation of the Autophagy Signaling Pathway
by: Xiang Gao, et al.
Published: (2023-01-01)

FOXG1 promotes osteogenesis of bone marrow-derived mesenchymal stem cells by activating autophagy through regulating USP14
by: Yiqi Zhang, et al.
Published: (2025-01-01)

Suppressing MicroRNA-30b by Estrogen Promotes Osteogenesis in Bone Marrow Mesenchymal Stem Cells
by: Guanqi Liu, et al.
Published: (2019-01-01)

An Injectable Kartogenin-Incorporated Hydrogel Supports Mesenchymal Stem Cells for Cartilage Tissue Engineering
by: Chongquan Huang, et al.
Published: (2025-04-01)

Exosomes from Kartogenin-Pretreated Infrapatellar Fat Pad Mesenchymal Stem Cells Enhance Chondrocyte Anabolism and Articular Cartilage Regeneration
by: Jiahua Shao, et al.
Published: (2021-01-01)

Correction: Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the SIRT1 pathway in aged bone marrow
by: Jie Song, et al.
Published: (2025-03-01)

The Differentiation Balance of Bone Marrow Mesenchymal Stem Cells Is Crucial to Hematopoiesis
by: Jiang Wu, et al.
Published: (2018-01-01)

Bone-Marrow-Derived Mesenchymal Stem Cells for Organ Repair
by: Ming Li, et al.
Published: (2013-01-01)

Lithium and Copper Induce the Osteogenesis-Angiogenesis Coupling of Bone Marrow Mesenchymal Stem Cells via Crosstalk between Canonical Wnt and HIF-1α Signaling Pathways
by: Zhen Tan, et al.
Published: (2021-01-01)

Photobiomodulation therapy at 650 nm enhances osteogenic differentiation of osteoporotic bone marrow mesenchymal stem cells through modulating autophagy
by: Haotian Li, et al.
Published: (2024-12-01)

Fluorinated Porcine Bone-Derived Hydroxyapatite Promotes Vascularized Osteogenesis by Coordinating Human Bone Marrow Mesenchymal Stem Cell/Human Umbilical Vein Endothelial Cell Complexes
by: Xiayi Wu, et al.
Published: (2024-12-01)

Ionizing radiation-mediated dendritic cell maturation exacerbates inflammatory response of bone marrow mesenchymal stem cells and impairs osteogenesis in radiation-induced jaw injury
by: Mengting Zheng, et al.
Published: (2025-07-01)

Glutamine Metabolism Is Essential for Stemness of Bone Marrow Mesenchymal Stem Cells and Bone Homeostasis
by: Tao Zhou, et al.
Published: (2019-01-01)

Fibrin Glue-Kartogenin Complex Promotes the Regeneration of the Tendon-Bone Interface in Rotator Cuff Injury
by: Jun Zhu, et al.
Published: (2021-01-01)

Deletion of p18INK4c enhances both osteogenesis and hematopoietic supportive capacity of bone marrow mesenchymal stromal cells
by: Wen Xing, et al.
Published: (2025-07-01)

Cell Fate and Differentiation of Bone Marrow Mesenchymal Stem Cells
by: Shoichiro Kokabu, et al.
Published: (2016-01-01)

Progress of bone marrow mesenchymal stem cell transplantation on neural plasticity in brain
by: Wenjing Li, et al.
Published: (2025-06-01)

The effect of resveratrol on the viability of rat bone marrow mesenchymal stem cells
by: Fatemeh Ghasemi, et al.
Published: (2024-12-01)

Enhanced Adipogenicity of Bone Marrow Mesenchymal Stem Cells in Aplastic Anemia
by: Naresh Kumar Tripathy, et al.
Published: (2014-01-01)

BONE MARROW MICROENVIRONMENT INVOLVEMENT IN T-MN: FOCUS ON MESENCHYMAL STEM CELLS
by: Maria Teresa Voso, et al.
Published: (2023-08-01)

Mesenchymal Stem Cells in Immune-Mediated Bone Marrow Failure Syndromes
by: Maria-Christina Kastrinaki, et al.
Published: (2013-01-01)

Characteristics of Mesenchymal Stem Cells Are Independent of Bone Marrow Storage Temperatures
by: Valentin Schrodi, et al.
Published: (2021-01-01)

Mobilization of Transplanted Bone Marrow Mesenchymal Stem Cells by Erythropoietin Facilitates the Reconstruction of Segmental Bone Defect
by: Jun Li, et al.
Published: (2019-01-01)

Bone marrow mesenchymal stem cell-derived extracellular vesicles alleviate diabetes-exacerbated atherosclerosis via AMPK/mTOR pathway-mediated autophagy-related macrophage polarization
by: Libo Liu, et al.
Published: (2025-01-01)

Bone marrow mesenchymal stem cell exosomes improve fracture union via remodeling metabolism in nonunion rat model
by: Cheng Li, et al.
Published: (2025-03-01)

Endothelial cell-derived exosomes trigger a positive feedback loop in osteogenesis-angiogenesis coupling via up-regulating zinc finger and BTB domain containing 16 in bone marrow mesenchymal stem cell
by: Lu Liu, et al.
Published: (2024-11-01)

RIPK1 Coordinates Bone Marrow Mesenchymal Stem Cell Survival by Maintaining Mitochondrial Homeostasis via p53
by: Qing Tian, et al.
Published: (2021-01-01)

Role of TGF-β3 and bone marrow mesenchymal stem cells on regeneration of myometrial injury in rats
by: Jing Yang, et al.
Published: (2022-12-01)

Extrachromosomal circular DNAs in the differentiation of human bone marrow mesenchymal stem cells
by: Yuxi Gu, et al.
Published: (2025-07-01)

Comparative Study on In Vitro Culture of Mouse Bone Marrow Mesenchymal Stem Cells
by: Yuxin Hu, et al.
Published: (2018-01-01)

Quality Evaluation of Human Bone Marrow Mesenchymal Stem Cells for Cartilage Repair
by: Katsunori Shiraishi, et al.
Published: (2017-01-01)

Study on the Dynamic Biological Characteristics of Human Bone Marrow Mesenchymal Stem Cell Senescence
by: Xiongbin Chen, et al.
Published: (2019-01-01)

Curcumin liposomes alleviate senescence of bone marrow mesenchymal stem cells by activating mitophagy
by: Weiyao Li, et al.
Published: (2024-12-01)

Bone Marrow Mesenchymal Stem Cells Inhibit Lipopolysaccharide-Induced Inflammatory Reactions in Macrophages and Endothelial Cells
by: Dequan Li, et al.
Published: (2016-01-01)

Comparison of infant bone marrow- and umbilical cord-derived mesenchymal stem cells in multilineage differentiation
by: Szu-Hsien Wu, et al.
Published: (2024-06-01)

PTHG2 Reduces Bone Loss in Ovariectomized Mice by Directing Bone Marrow Mesenchymal Stem Cell Fate
by: Jiao Chen, et al.
Published: (2021-01-01)

Ox-LDL Promotes Migration and Adhesion of Bone Marrow-Derived Mesenchymal Stem Cells via Regulation of MCP-1 Expression
by: Fenxi Zhang, et al.
Published: (2013-01-01)

Bone marrow mesenchymal stem cells transport connexin43 via tunneling nanotubes to alleviate isopreterenol-induced myocardial hypertrophy
by: Jianghui Zhang, et al.
Published: (2025-05-01)

Transplantation of Bone Marrow-Derived Mesenchymal Stem Cells Promotes Delayed Wound Healing in Diabetic Rats
by: Jiangbo Wan, et al.
Published: (2013-01-01)

Infusion of Bone Marrow Mesenchymal Stem Cells Attenuates Experimental Severe Acute Pancreatitis in Rats
by: Hang Zhao, et al.
Published: (2016-01-01)