Reference Interval of Hemoglobin A1c and Influence of Hematological Parameters on Its Serum Concentration in Dogs
HbA1c could be an alternative to fructosamine as a marker for glucose levels over a longer period. In this study, we calculated a reference interval for HbA1c in dogs and investigated the correlation of HbA1c with hemoglobin and different hematological parameters. In total, 110 blood samples from do...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Veterinary Medicine International |
| Online Access: | http://dx.doi.org/10.1155/2020/7150901 |
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| author | Stephan Neumann |
| author_facet | Stephan Neumann |
| author_sort | Stephan Neumann |
| collection | DOAJ |
| description | HbA1c could be an alternative to fructosamine as a marker for glucose levels over a longer period. In this study, we calculated a reference interval for HbA1c in dogs and investigated the correlation of HbA1c with hemoglobin and different hematological parameters. In total, 110 blood samples from dogs were investigated. Significant negative correlations were found between HbA1c and erythrocyte count, hemoglobin concentration, as well as hematocrit. There was a tendency in the red cell distribution width. No significant correlation was found in the reticulocyte number and the erythrocyte indices. In conclusion, there is an association of different blood parameters with the HbA1c concentration, which have to be considered for the interpretation of HbA1c. |
| format | Article |
| id | doaj-art-3809f33b74734e4e88dfbe5bee5dc93d |
| institution | Kabale University |
| issn | 2090-8113 2042-0048 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Veterinary Medicine International |
| spelling | doaj-art-3809f33b74734e4e88dfbe5bee5dc93d2025-02-03T06:46:30ZengWileyVeterinary Medicine International2090-81132042-00482020-01-01202010.1155/2020/71509017150901Reference Interval of Hemoglobin A1c and Influence of Hematological Parameters on Its Serum Concentration in DogsStephan Neumann0Small Animal Clinic, Institute of Veterinary Medicine, University of Goettingen, Burckhardtweg 2, D-37077, Goettingen, GermanyHbA1c could be an alternative to fructosamine as a marker for glucose levels over a longer period. In this study, we calculated a reference interval for HbA1c in dogs and investigated the correlation of HbA1c with hemoglobin and different hematological parameters. In total, 110 blood samples from dogs were investigated. Significant negative correlations were found between HbA1c and erythrocyte count, hemoglobin concentration, as well as hematocrit. There was a tendency in the red cell distribution width. No significant correlation was found in the reticulocyte number and the erythrocyte indices. In conclusion, there is an association of different blood parameters with the HbA1c concentration, which have to be considered for the interpretation of HbA1c.http://dx.doi.org/10.1155/2020/7150901 |
| spellingShingle | Stephan Neumann Reference Interval of Hemoglobin A1c and Influence of Hematological Parameters on Its Serum Concentration in Dogs Veterinary Medicine International |
| title | Reference Interval of Hemoglobin A1c and Influence of Hematological Parameters on Its Serum Concentration in Dogs |
| title_full | Reference Interval of Hemoglobin A1c and Influence of Hematological Parameters on Its Serum Concentration in Dogs |
| title_fullStr | Reference Interval of Hemoglobin A1c and Influence of Hematological Parameters on Its Serum Concentration in Dogs |
| title_full_unstemmed | Reference Interval of Hemoglobin A1c and Influence of Hematological Parameters on Its Serum Concentration in Dogs |
| title_short | Reference Interval of Hemoglobin A1c and Influence of Hematological Parameters on Its Serum Concentration in Dogs |
| title_sort | reference interval of hemoglobin a1c and influence of hematological parameters on its serum concentration in dogs |
| url | http://dx.doi.org/10.1155/2020/7150901 |
| work_keys_str_mv | AT stephanneumann referenceintervalofhemoglobina1candinfluenceofhematologicalparametersonitsserumconcentrationindogs |