Ovarian Volume Correlates Strongly with the Number of Nongrowing Follicles in the Human Ovary
A reliable indirect measure of ovarian reserve for the individual woman remains a challenge for reproductive specialists. Using descriptive statistics from a large-scale study of ovarian volumes, we have developed a normative model for healthy females for ages 25 through 85. For average values, this...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/2012/305025 |
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| author | Thomas W. Kelsey W. Hamish B. Wallace |
| author_facet | Thomas W. Kelsey W. Hamish B. Wallace |
| author_sort | Thomas W. Kelsey |
| collection | DOAJ |
| description | A reliable indirect measure of ovarian reserve for the individual woman remains a challenge for reproductive specialists. Using descriptive statistics from a large-scale study of ovarian volumes, we have developed a normative model for healthy females for ages 25 through 85. For average values, this model has a strong and positive correlation (r=0.89) with our recent model of nongrowing follicles (NGFs) in the human ovary for ages 25 through 51. When both models are log-adjusted, the correlation increases to r=0.99, over the full range of ovarian volume. Furthermore we can deduce that an ovary of 3 cm3 volume (or less) contains approximately 1000 NGF (or fewer). These strong correlations indicate that ovarian volume is a useful factor in the indirect estimation of human ovarian reserve for the individual woman. |
| format | Article |
| id | doaj-art-380486d429994117813583838c5984bf |
| institution | Kabale University |
| issn | 1687-9589 1687-9597 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obstetrics and Gynecology International |
| spelling | doaj-art-380486d429994117813583838c5984bf2025-02-03T01:21:37ZengWileyObstetrics and Gynecology International1687-95891687-95972012-01-01201210.1155/2012/305025305025Ovarian Volume Correlates Strongly with the Number of Nongrowing Follicles in the Human OvaryThomas W. Kelsey0W. Hamish B. Wallace1School of Computer Science, University of St. Andrews, St. Andrews, Scotland, Kelsey KY16 9SX, UKDivision of Reproductive and Developmental Sciences, University of Edinburgh, Edinburgh, Scotland, Wallace EH9 1LW, UKA reliable indirect measure of ovarian reserve for the individual woman remains a challenge for reproductive specialists. Using descriptive statistics from a large-scale study of ovarian volumes, we have developed a normative model for healthy females for ages 25 through 85. For average values, this model has a strong and positive correlation (r=0.89) with our recent model of nongrowing follicles (NGFs) in the human ovary for ages 25 through 51. When both models are log-adjusted, the correlation increases to r=0.99, over the full range of ovarian volume. Furthermore we can deduce that an ovary of 3 cm3 volume (or less) contains approximately 1000 NGF (or fewer). These strong correlations indicate that ovarian volume is a useful factor in the indirect estimation of human ovarian reserve for the individual woman.http://dx.doi.org/10.1155/2012/305025 |
| spellingShingle | Thomas W. Kelsey W. Hamish B. Wallace Ovarian Volume Correlates Strongly with the Number of Nongrowing Follicles in the Human Ovary Obstetrics and Gynecology International |
| title | Ovarian Volume Correlates Strongly with the Number of Nongrowing Follicles in the Human Ovary |
| title_full | Ovarian Volume Correlates Strongly with the Number of Nongrowing Follicles in the Human Ovary |
| title_fullStr | Ovarian Volume Correlates Strongly with the Number of Nongrowing Follicles in the Human Ovary |
| title_full_unstemmed | Ovarian Volume Correlates Strongly with the Number of Nongrowing Follicles in the Human Ovary |
| title_short | Ovarian Volume Correlates Strongly with the Number of Nongrowing Follicles in the Human Ovary |
| title_sort | ovarian volume correlates strongly with the number of nongrowing follicles in the human ovary |
| url | http://dx.doi.org/10.1155/2012/305025 |
| work_keys_str_mv | AT thomaswkelsey ovarianvolumecorrelatesstronglywiththenumberofnongrowingfolliclesinthehumanovary AT whamishbwallace ovarianvolumecorrelatesstronglywiththenumberofnongrowingfolliclesinthehumanovary |