Ovarian Volume Correlates Strongly with the Number of Nongrowing Follicles in the Human Ovary
A reliable indirect measure of ovarian reserve for the individual woman remains a challenge for reproductive specialists. Using descriptive statistics from a large-scale study of ovarian volumes, we have developed a normative model for healthy females for ages 25 through 85. For average values, this...
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Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | Obstetrics and Gynecology International |
Online Access: | http://dx.doi.org/10.1155/2012/305025 |
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Summary: | A reliable indirect measure of ovarian reserve for the individual woman remains a challenge for reproductive specialists. Using descriptive statistics from a large-scale study of ovarian volumes, we have developed a normative model for healthy females for ages 25 through 85. For average values, this model has a strong and positive correlation (r=0.89) with our recent model of nongrowing follicles (NGFs) in the human ovary for ages 25 through 51. When both models are log-adjusted, the correlation increases to r=0.99, over the full range of ovarian volume. Furthermore we can deduce that an ovary of 3 cm3 volume (or less) contains approximately 1000 NGF (or fewer). These strong correlations indicate that ovarian volume is a useful factor in the indirect estimation of human ovarian reserve for the individual woman. |
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ISSN: | 1687-9589 1687-9597 |