Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review
Colorectal cancer (CRC), one of the leading causes of cancer-related deaths, presents with challenging features related to its diagnosis and management. The incidence of CRC in the adolescent and young adult (AYA) population has increased over the past couple of decades despite the decline in the ov...
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Format: | Article |
Language: | English |
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Wiley
2019-01-01
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Series: | Case Reports in Oncological Medicine |
Online Access: | http://dx.doi.org/10.1155/2019/3092674 |
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author | Farida Abi Farraj Hadi Sabbagh Tarek Aridi Najla Fakhruddin Fadi Farhat |
author_facet | Farida Abi Farraj Hadi Sabbagh Tarek Aridi Najla Fakhruddin Fadi Farhat |
author_sort | Farida Abi Farraj |
collection | DOAJ |
description | Colorectal cancer (CRC), one of the leading causes of cancer-related deaths, presents with challenging features related to its diagnosis and management. The incidence of CRC in the adolescent and young adult (AYA) population has increased over the past couple of decades despite the decline in the overall occurrence of CRC in the general population. Signet ring cell carcinoma is one of the rare histopathologic subtypes of CRC; however, it is more prevalent in AYA patients than in older adults and presents with unconventional histologic characteristics, a distinct clinical behavior, and a poor prognosis. We report a case of a primary signet ring cell adenocarcinoma of the ascending colon in a 19-year-old male who presented with unusual signs and symptoms and was diagnosed with stage IVA (T4a N0 M1, with peritoneal seeding). The unusual presentation and location of the tumor in this case warrant further investigation. |
format | Article |
id | doaj-art-37f95973945f454690110c9000ab646d |
institution | Kabale University |
issn | 2090-6706 2090-6714 |
language | English |
publishDate | 2019-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Oncological Medicine |
spelling | doaj-art-37f95973945f454690110c9000ab646d2025-02-03T01:24:16ZengWileyCase Reports in Oncological Medicine2090-67062090-67142019-01-01201910.1155/2019/30926743092674Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature ReviewFarida Abi Farraj0Hadi Sabbagh1Tarek Aridi2Najla Fakhruddin3Fadi Farhat4Faculty of Medicine, American University of Beirut, Beirut, LebanonFaculty of Medicine, American University of Beirut, Beirut, LebanonFaculty of Medicine, American University of Beirut, Beirut, LebanonDepartment of Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, LebanonDepartment of Oncology, Hammoud Hospital University Medical Center, Saida, LebanonColorectal cancer (CRC), one of the leading causes of cancer-related deaths, presents with challenging features related to its diagnosis and management. The incidence of CRC in the adolescent and young adult (AYA) population has increased over the past couple of decades despite the decline in the overall occurrence of CRC in the general population. Signet ring cell carcinoma is one of the rare histopathologic subtypes of CRC; however, it is more prevalent in AYA patients than in older adults and presents with unconventional histologic characteristics, a distinct clinical behavior, and a poor prognosis. We report a case of a primary signet ring cell adenocarcinoma of the ascending colon in a 19-year-old male who presented with unusual signs and symptoms and was diagnosed with stage IVA (T4a N0 M1, with peritoneal seeding). The unusual presentation and location of the tumor in this case warrant further investigation.http://dx.doi.org/10.1155/2019/3092674 |
spellingShingle | Farida Abi Farraj Hadi Sabbagh Tarek Aridi Najla Fakhruddin Fadi Farhat Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review Case Reports in Oncological Medicine |
title | Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review |
title_full | Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review |
title_fullStr | Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review |
title_full_unstemmed | Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review |
title_short | Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review |
title_sort | signet ring cell carcinoma of the colon in young adults a case report and literature review |
url | http://dx.doi.org/10.1155/2019/3092674 |
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