Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review

Colorectal cancer (CRC), one of the leading causes of cancer-related deaths, presents with challenging features related to its diagnosis and management. The incidence of CRC in the adolescent and young adult (AYA) population has increased over the past couple of decades despite the decline in the ov...

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Main Authors: Farida Abi Farraj, Hadi Sabbagh, Tarek Aridi, Najla Fakhruddin, Fadi Farhat
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2019/3092674
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author Farida Abi Farraj
Hadi Sabbagh
Tarek Aridi
Najla Fakhruddin
Fadi Farhat
author_facet Farida Abi Farraj
Hadi Sabbagh
Tarek Aridi
Najla Fakhruddin
Fadi Farhat
author_sort Farida Abi Farraj
collection DOAJ
description Colorectal cancer (CRC), one of the leading causes of cancer-related deaths, presents with challenging features related to its diagnosis and management. The incidence of CRC in the adolescent and young adult (AYA) population has increased over the past couple of decades despite the decline in the overall occurrence of CRC in the general population. Signet ring cell carcinoma is one of the rare histopathologic subtypes of CRC; however, it is more prevalent in AYA patients than in older adults and presents with unconventional histologic characteristics, a distinct clinical behavior, and a poor prognosis. We report a case of a primary signet ring cell adenocarcinoma of the ascending colon in a 19-year-old male who presented with unusual signs and symptoms and was diagnosed with stage IVA (T4a N0 M1, with peritoneal seeding). The unusual presentation and location of the tumor in this case warrant further investigation.
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institution Kabale University
issn 2090-6706
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language English
publishDate 2019-01-01
publisher Wiley
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series Case Reports in Oncological Medicine
spelling doaj-art-37f95973945f454690110c9000ab646d2025-02-03T01:24:16ZengWileyCase Reports in Oncological Medicine2090-67062090-67142019-01-01201910.1155/2019/30926743092674Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature ReviewFarida Abi Farraj0Hadi Sabbagh1Tarek Aridi2Najla Fakhruddin3Fadi Farhat4Faculty of Medicine, American University of Beirut, Beirut, LebanonFaculty of Medicine, American University of Beirut, Beirut, LebanonFaculty of Medicine, American University of Beirut, Beirut, LebanonDepartment of Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, LebanonDepartment of Oncology, Hammoud Hospital University Medical Center, Saida, LebanonColorectal cancer (CRC), one of the leading causes of cancer-related deaths, presents with challenging features related to its diagnosis and management. The incidence of CRC in the adolescent and young adult (AYA) population has increased over the past couple of decades despite the decline in the overall occurrence of CRC in the general population. Signet ring cell carcinoma is one of the rare histopathologic subtypes of CRC; however, it is more prevalent in AYA patients than in older adults and presents with unconventional histologic characteristics, a distinct clinical behavior, and a poor prognosis. We report a case of a primary signet ring cell adenocarcinoma of the ascending colon in a 19-year-old male who presented with unusual signs and symptoms and was diagnosed with stage IVA (T4a N0 M1, with peritoneal seeding). The unusual presentation and location of the tumor in this case warrant further investigation.http://dx.doi.org/10.1155/2019/3092674
spellingShingle Farida Abi Farraj
Hadi Sabbagh
Tarek Aridi
Najla Fakhruddin
Fadi Farhat
Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review
Case Reports in Oncological Medicine
title Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review
title_full Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review
title_fullStr Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review
title_full_unstemmed Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review
title_short Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review
title_sort signet ring cell carcinoma of the colon in young adults a case report and literature review
url http://dx.doi.org/10.1155/2019/3092674
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