A Review of Herbal Treatment for Functional Gastrointestinal Disorders and Infection

Functional dyspepsia (FD), a common gastrointestinal condition, poses significant burdens on both individuals and society. In this article, we conducted PubMed searches using specific keywords to review clinical trials focusing on conventional and herbal treatments for dyspepsia as well as the adve...

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Main Authors: Krupavaram B, A Kishore Babu, Santhiya Manickam Pillay, Tan Ching Siang, Bama V. V. Menon, Ganesh Sritheran Paneerselvam, Long Chiau Ming, Yaser Mohammed Al-Worafi, Wen Han Chooi
Format: Article
Language:English
Published: HH Publisher 2023-10-01
Series:Progress in Microbes and Molecular Biology
Online Access:https://journals.hh-publisher.com/index.php/pmmb/article/view/875
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author Krupavaram B
A Kishore Babu
Santhiya Manickam Pillay
Tan Ching Siang
Bama V. V. Menon
Ganesh Sritheran Paneerselvam
Long Chiau Ming
Yaser Mohammed Al-Worafi
Wen Han Chooi
author_facet Krupavaram B
A Kishore Babu
Santhiya Manickam Pillay
Tan Ching Siang
Bama V. V. Menon
Ganesh Sritheran Paneerselvam
Long Chiau Ming
Yaser Mohammed Al-Worafi
Wen Han Chooi
author_sort Krupavaram B
collection DOAJ
description Functional dyspepsia (FD), a common gastrointestinal condition, poses significant burdens on both individuals and society. In this article, we conducted PubMed searches using specific keywords to review clinical trials focusing on conventional and herbal treatments for dyspepsia as well as the adverse effects of non-herbal treatments. Dyspepsia can be managed using proton pump inhibitors, H2 blockers, and antacids. Additionally, we explore Tegaserod, a partial agonist of the 5-HT4 receptor, in the context of prokinetic medications. We summarise the research supporting the effectiveness of non-herbal dyspepsia treatment, considering factors beyond acid reduction, such as the placebo effect and the variability of dyspepsia symptoms, as discussed in the section on proton pump inhibitor (PPI) medication. Unlike most pharmacotherapies targeting a single mechanism, herbal medications often contain multiple active ingredients that can address several signalling pathways simultaneously. Notable herbs like fennel, cumin, aloe vera, ginger, and licorice have documented uses in the literature. Whether derived from a single plant or a combination, herbal treatments hold promises for addressing multiple conditions simultaneously. Therefore, evaluating herbal therapy at all stages of development should adhere to the same scientific rigour applied to chemically specific therapies.
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spelling doaj-art-37e0525520504e53a58b83f72fc115292025-02-04T08:39:49ZengHH PublisherProgress in Microbes and Molecular Biology2637-10492023-10-016110.36877/pmmb.a0000346A Review of Herbal Treatment for Functional Gastrointestinal Disorders and InfectionKrupavaram BA Kishore BabuSanthiya Manickam PillayTan Ching SiangBama V. V. MenonGanesh Sritheran PaneerselvamLong Chiau MingYaser Mohammed Al-WorafiWen Han Chooi Functional dyspepsia (FD), a common gastrointestinal condition, poses significant burdens on both individuals and society. In this article, we conducted PubMed searches using specific keywords to review clinical trials focusing on conventional and herbal treatments for dyspepsia as well as the adverse effects of non-herbal treatments. Dyspepsia can be managed using proton pump inhibitors, H2 blockers, and antacids. Additionally, we explore Tegaserod, a partial agonist of the 5-HT4 receptor, in the context of prokinetic medications. We summarise the research supporting the effectiveness of non-herbal dyspepsia treatment, considering factors beyond acid reduction, such as the placebo effect and the variability of dyspepsia symptoms, as discussed in the section on proton pump inhibitor (PPI) medication. Unlike most pharmacotherapies targeting a single mechanism, herbal medications often contain multiple active ingredients that can address several signalling pathways simultaneously. Notable herbs like fennel, cumin, aloe vera, ginger, and licorice have documented uses in the literature. Whether derived from a single plant or a combination, herbal treatments hold promises for addressing multiple conditions simultaneously. Therefore, evaluating herbal therapy at all stages of development should adhere to the same scientific rigour applied to chemically specific therapies. https://journals.hh-publisher.com/index.php/pmmb/article/view/875
spellingShingle Krupavaram B
A Kishore Babu
Santhiya Manickam Pillay
Tan Ching Siang
Bama V. V. Menon
Ganesh Sritheran Paneerselvam
Long Chiau Ming
Yaser Mohammed Al-Worafi
Wen Han Chooi
A Review of Herbal Treatment for Functional Gastrointestinal Disorders and Infection
Progress in Microbes and Molecular Biology
title A Review of Herbal Treatment for Functional Gastrointestinal Disorders and Infection
title_full A Review of Herbal Treatment for Functional Gastrointestinal Disorders and Infection
title_fullStr A Review of Herbal Treatment for Functional Gastrointestinal Disorders and Infection
title_full_unstemmed A Review of Herbal Treatment for Functional Gastrointestinal Disorders and Infection
title_short A Review of Herbal Treatment for Functional Gastrointestinal Disorders and Infection
title_sort review of herbal treatment for functional gastrointestinal disorders and infection
url https://journals.hh-publisher.com/index.php/pmmb/article/view/875
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