Epigenetic Modifiers: Exploring the Roles of Histone Methyltransferases and Demethylases in Cancer and Neurodegeneration

Histone methyltransferases (HMTs) and histone demethylases (HDMs) are critical enzymes that regulate chromatin dynamics and gene expression through the addition and removal of methyl groups on histone proteins. HMTs, such as PRC2 and SETD2, are involved in the trimethylation of histone H3 at lysine...

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Bibliographic Details
Main Authors: Lauren Reed, Janak Abraham, Shay Patel, Shilpa S. Dhar
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biology
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Online Access:https://www.mdpi.com/2079-7737/13/12/1008
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