Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology
Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus (DM) causing vision impairment even at young ages. There are numerous mechanisms involved in its development such as inflammation and cellular degeneration leading to endothelial and neural damage. These mechanism...
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Format: | Article |
Language: | English |
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Wiley
2019-01-01
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Series: | Journal of Diabetes Research |
Online Access: | http://dx.doi.org/10.1155/2019/8562408 |
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author | Olvera-Montaño Cecilia Castellanos-González José Alberto Navarro-Partida José Cardona-Muñoz Ernesto Germán López-Contreras Ana Karen Roman-Pintos Luis Miguel Robles-Rivera Ricardo Raúl Rodríguez-Carrizalez Adolfo Daniel |
author_facet | Olvera-Montaño Cecilia Castellanos-González José Alberto Navarro-Partida José Cardona-Muñoz Ernesto Germán López-Contreras Ana Karen Roman-Pintos Luis Miguel Robles-Rivera Ricardo Raúl Rodríguez-Carrizalez Adolfo Daniel |
author_sort | Olvera-Montaño Cecilia |
collection | DOAJ |
description | Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus (DM) causing vision impairment even at young ages. There are numerous mechanisms involved in its development such as inflammation and cellular degeneration leading to endothelial and neural damage. These mechanisms are interlinked thus worsening the diabetic retinopathy outcome. In this review, we propose oxidative stress as the focus point of this complication onset. |
format | Article |
id | doaj-art-37b59bf8ab1942468bf371d581bbb852 |
institution | Kabale University |
issn | 2314-6745 2314-6753 |
language | English |
publishDate | 2019-01-01 |
publisher | Wiley |
record_format | Article |
series | Journal of Diabetes Research |
spelling | doaj-art-37b59bf8ab1942468bf371d581bbb8522025-02-03T05:43:56ZengWileyJournal of Diabetes Research2314-67452314-67532019-01-01201910.1155/2019/85624088562408Oxidative Stress as the Main Target in Diabetic Retinopathy PathophysiologyOlvera-Montaño Cecilia0Castellanos-González José Alberto1Navarro-Partida José2Cardona-Muñoz Ernesto Germán3López-Contreras Ana Karen4Roman-Pintos Luis Miguel5Robles-Rivera Ricardo Raúl6Rodríguez-Carrizalez Adolfo Daniel7Institute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, MexicoDepartment of Ophthalmology, Specialties Hospital of the National Occidental Medical Center, Mexican Institute of Social Security, MexicoTecnológico de Monterrey Institute, School of Medicine and Health Sciences, Campus Guadalajara, MexicoInstitute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, MexicoInstitute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, MexicoDepartment of Physiology, University Center of Tonalá, University of Guadalajara, MexicoInstitute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, MexicoInstitute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, MexicoDiabetic retinopathy (DR) is one of the most common complications of diabetes mellitus (DM) causing vision impairment even at young ages. There are numerous mechanisms involved in its development such as inflammation and cellular degeneration leading to endothelial and neural damage. These mechanisms are interlinked thus worsening the diabetic retinopathy outcome. In this review, we propose oxidative stress as the focus point of this complication onset.http://dx.doi.org/10.1155/2019/8562408 |
spellingShingle | Olvera-Montaño Cecilia Castellanos-González José Alberto Navarro-Partida José Cardona-Muñoz Ernesto Germán López-Contreras Ana Karen Roman-Pintos Luis Miguel Robles-Rivera Ricardo Raúl Rodríguez-Carrizalez Adolfo Daniel Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology Journal of Diabetes Research |
title | Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology |
title_full | Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology |
title_fullStr | Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology |
title_full_unstemmed | Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology |
title_short | Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology |
title_sort | oxidative stress as the main target in diabetic retinopathy pathophysiology |
url | http://dx.doi.org/10.1155/2019/8562408 |
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