Spontaneous and Excellent Healing of Bilateral Brown Tumors in Mandible after Endocrinal Therapy and Subtotal Parathyroidectomy: Case Report with 4-Year Follow-Up

Primary hyperparathyroidism is an endocrine disorder occurring due to increased secretion of parathormone resulting in a complex of clinical, anatomical, and biochemical alterations. On the other hand, excision of a parathyroid adenoma can normalize the metabolic status. A 24-year-old man was referr...

Full description

Saved in:
Bibliographic Details
Main Authors: Turker Yucesoy, Erdem Kilic, Fatma Dogruel, Fahri Bayram, Alper Alkan, Alper Celal Akcan, Figen Ozturk
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2018/8070131
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832547001018875904
author Turker Yucesoy
Erdem Kilic
Fatma Dogruel
Fahri Bayram
Alper Alkan
Alper Celal Akcan
Figen Ozturk
author_facet Turker Yucesoy
Erdem Kilic
Fatma Dogruel
Fahri Bayram
Alper Alkan
Alper Celal Akcan
Figen Ozturk
author_sort Turker Yucesoy
collection DOAJ
description Primary hyperparathyroidism is an endocrine disorder occurring due to increased secretion of parathormone resulting in a complex of clinical, anatomical, and biochemical alterations. On the other hand, excision of a parathyroid adenoma can normalize the metabolic status. A 24-year-old man was referred to the hospital with bilateral swelling and spontaneous gingival bleeding from posterior of the mandible also with radiolucent well-demarcated lesions bilaterally in the mandibular third molar regions. After consultations, the patient was hospitalized in the endocrinology department where further tests were performed due to highly increased PTH level as 714 pg/ml. Bilateral brown tumors started to regress spontaneously, and no additional surgery was required after subtotal parathyroidectomy was performed. The presented case is the first patient whose bilateral brown tumors in the jaws spontaneously and totally healed after subtotal parathyroidectomy and endocrinal therapy who was strictly followed up for 4 years even though the lesions were associated with impacted third molars.
format Article
id doaj-art-37af439800d84993bd363e83727db85b
institution Kabale University
issn 2090-6447
2090-6455
language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Case Reports in Dentistry
spelling doaj-art-37af439800d84993bd363e83727db85b2025-02-03T06:46:17ZengWileyCase Reports in Dentistry2090-64472090-64552018-01-01201810.1155/2018/80701318070131Spontaneous and Excellent Healing of Bilateral Brown Tumors in Mandible after Endocrinal Therapy and Subtotal Parathyroidectomy: Case Report with 4-Year Follow-UpTurker Yucesoy0Erdem Kilic1Fatma Dogruel2Fahri Bayram3Alper Alkan4Alper Celal Akcan5Figen Ozturk6Oral and Maxillofacial Surgery Department, Dentistry Faculty, Bezmialem Vakif University, Istanbul, TurkeyOral and Maxillofacial Surgery Department, Dentistry Faculty, Bezmialem Vakif University, Istanbul, TurkeyOral and Maxillofacial Surgery Department, Dentistry Faculty, Erciyes University, Kayseri, TurkeyEndocrinology Department, Medicine Faculty, Erciyes University, Kayseri, TurkeyOral and Maxillofacial Surgery Department, Dentistry Faculty, Bezmialem Vakif University, Istanbul, TurkeyGeneral Surgery Department, Medicine Faculty, Erciyes University, Kayseri, TurkeyPathology Department, Medicine Faculty, Erciyes University, Kayseri, TurkeyPrimary hyperparathyroidism is an endocrine disorder occurring due to increased secretion of parathormone resulting in a complex of clinical, anatomical, and biochemical alterations. On the other hand, excision of a parathyroid adenoma can normalize the metabolic status. A 24-year-old man was referred to the hospital with bilateral swelling and spontaneous gingival bleeding from posterior of the mandible also with radiolucent well-demarcated lesions bilaterally in the mandibular third molar regions. After consultations, the patient was hospitalized in the endocrinology department where further tests were performed due to highly increased PTH level as 714 pg/ml. Bilateral brown tumors started to regress spontaneously, and no additional surgery was required after subtotal parathyroidectomy was performed. The presented case is the first patient whose bilateral brown tumors in the jaws spontaneously and totally healed after subtotal parathyroidectomy and endocrinal therapy who was strictly followed up for 4 years even though the lesions were associated with impacted third molars.http://dx.doi.org/10.1155/2018/8070131
spellingShingle Turker Yucesoy
Erdem Kilic
Fatma Dogruel
Fahri Bayram
Alper Alkan
Alper Celal Akcan
Figen Ozturk
Spontaneous and Excellent Healing of Bilateral Brown Tumors in Mandible after Endocrinal Therapy and Subtotal Parathyroidectomy: Case Report with 4-Year Follow-Up
Case Reports in Dentistry
title Spontaneous and Excellent Healing of Bilateral Brown Tumors in Mandible after Endocrinal Therapy and Subtotal Parathyroidectomy: Case Report with 4-Year Follow-Up
title_full Spontaneous and Excellent Healing of Bilateral Brown Tumors in Mandible after Endocrinal Therapy and Subtotal Parathyroidectomy: Case Report with 4-Year Follow-Up
title_fullStr Spontaneous and Excellent Healing of Bilateral Brown Tumors in Mandible after Endocrinal Therapy and Subtotal Parathyroidectomy: Case Report with 4-Year Follow-Up
title_full_unstemmed Spontaneous and Excellent Healing of Bilateral Brown Tumors in Mandible after Endocrinal Therapy and Subtotal Parathyroidectomy: Case Report with 4-Year Follow-Up
title_short Spontaneous and Excellent Healing of Bilateral Brown Tumors in Mandible after Endocrinal Therapy and Subtotal Parathyroidectomy: Case Report with 4-Year Follow-Up
title_sort spontaneous and excellent healing of bilateral brown tumors in mandible after endocrinal therapy and subtotal parathyroidectomy case report with 4 year follow up
url http://dx.doi.org/10.1155/2018/8070131
work_keys_str_mv AT turkeryucesoy spontaneousandexcellenthealingofbilateralbrowntumorsinmandibleafterendocrinaltherapyandsubtotalparathyroidectomycasereportwith4yearfollowup
AT erdemkilic spontaneousandexcellenthealingofbilateralbrowntumorsinmandibleafterendocrinaltherapyandsubtotalparathyroidectomycasereportwith4yearfollowup
AT fatmadogruel spontaneousandexcellenthealingofbilateralbrowntumorsinmandibleafterendocrinaltherapyandsubtotalparathyroidectomycasereportwith4yearfollowup
AT fahribayram spontaneousandexcellenthealingofbilateralbrowntumorsinmandibleafterendocrinaltherapyandsubtotalparathyroidectomycasereportwith4yearfollowup
AT alperalkan spontaneousandexcellenthealingofbilateralbrowntumorsinmandibleafterendocrinaltherapyandsubtotalparathyroidectomycasereportwith4yearfollowup
AT alpercelalakcan spontaneousandexcellenthealingofbilateralbrowntumorsinmandibleafterendocrinaltherapyandsubtotalparathyroidectomycasereportwith4yearfollowup
AT figenozturk spontaneousandexcellenthealingofbilateralbrowntumorsinmandibleafterendocrinaltherapyandsubtotalparathyroidectomycasereportwith4yearfollowup