Disrupting of IGF2BP3-stabilized CLDN11 mRNA by TNF-α increases intestinal permeability in obesity-related severe acute pancreatitis
Abstract Background Obesity is a significant risk factor for severe acute pancreatitis (SAP) and is typically associated with increased intestinal permeability. Understanding the role of specific molecules can help reduce the risk of developing SAP. Claudin 11 (CLDN11), a member of the Claudin famil...
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Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s10020-025-01078-9 |
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