Kimura disease: A rare presentation in the rheumatology clinic
Kimura disease (KD) is a rare chronic inflammatory disorder of unknown cause, primarily seen in young Asian males. The disease is characterized by painless subcutaneous swelling in head and neck region, accompanied by regional lymphadenopathy and frequent salivary gland enlargement. Blood and tissue...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2020-01-01
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| Series: | Indian Journal of Rheumatology |
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| Online Access: | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2020;volume=15;issue=4;spage=347;epage=353;aulast=Kumar |
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| author | Malay Kumar Arun Hegde Gunjan Dwivedi Prashant Sengupta Kovilapu Uday Bhanu |
| author_facet | Malay Kumar Arun Hegde Gunjan Dwivedi Prashant Sengupta Kovilapu Uday Bhanu |
| author_sort | Malay Kumar |
| collection | DOAJ |
| description | Kimura disease (KD) is a rare chronic inflammatory disorder of unknown cause, primarily seen in young Asian males. The disease is characterized by painless subcutaneous swelling in head and neck region, accompanied by regional lymphadenopathy and frequent salivary gland enlargement. Blood and tissue eosinophilia, and elevated immunoglobulin E (IgE) levels, are common associations. Characteristic histopathological findings of biopsy specimens obtained from the subcutaneous swellings or lymph nodes include eosinophilic infiltrates, follicular hyperplasia, and proliferation of postcapillary venules. The course is usually waxing and waning, albeit benign. Early diagnosis may spare the patient from unnecessary invasive procedures. We herein, describe a case of KD in an 18 years old male, who presented with subcutaneous swelling in the both cheek (right more than left) in 2014, underwent multiple surgical interventions for the same, before being reassessed and finally diagnosed as KD in 2020, based upon peripheral blood eosinophilia, raised serum IgE levels and histopathological findings. He subsequently made a good recovery on oral steroids. |
| format | Article |
| id | doaj-art-3785fe51e26a4a31acced09bfd4c3ac3 |
| institution | Kabale University |
| issn | 0973-3698 0973-3701 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Indian Journal of Rheumatology |
| spelling | doaj-art-3785fe51e26a4a31acced09bfd4c3ac32025-02-03T10:55:21ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012020-01-0115434735310.4103/injr.injr_132_20Kimura disease: A rare presentation in the rheumatology clinicMalay KumarArun HegdeGunjan DwivediPrashant SenguptaKovilapu Uday BhanuKimura disease (KD) is a rare chronic inflammatory disorder of unknown cause, primarily seen in young Asian males. The disease is characterized by painless subcutaneous swelling in head and neck region, accompanied by regional lymphadenopathy and frequent salivary gland enlargement. Blood and tissue eosinophilia, and elevated immunoglobulin E (IgE) levels, are common associations. Characteristic histopathological findings of biopsy specimens obtained from the subcutaneous swellings or lymph nodes include eosinophilic infiltrates, follicular hyperplasia, and proliferation of postcapillary venules. The course is usually waxing and waning, albeit benign. Early diagnosis may spare the patient from unnecessary invasive procedures. We herein, describe a case of KD in an 18 years old male, who presented with subcutaneous swelling in the both cheek (right more than left) in 2014, underwent multiple surgical interventions for the same, before being reassessed and finally diagnosed as KD in 2020, based upon peripheral blood eosinophilia, raised serum IgE levels and histopathological findings. He subsequently made a good recovery on oral steroids.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2020;volume=15;issue=4;spage=347;epage=353;aulast=Kumarangiolymphoid hyperplasia with eosinophiliaeosinophiliaimmunoglobulin ekimura diseasesubcutaneous cheek swelling |
| spellingShingle | Malay Kumar Arun Hegde Gunjan Dwivedi Prashant Sengupta Kovilapu Uday Bhanu Kimura disease: A rare presentation in the rheumatology clinic Indian Journal of Rheumatology angiolymphoid hyperplasia with eosinophilia eosinophilia immunoglobulin e kimura disease subcutaneous cheek swelling |
| title | Kimura disease: A rare presentation in the rheumatology clinic |
| title_full | Kimura disease: A rare presentation in the rheumatology clinic |
| title_fullStr | Kimura disease: A rare presentation in the rheumatology clinic |
| title_full_unstemmed | Kimura disease: A rare presentation in the rheumatology clinic |
| title_short | Kimura disease: A rare presentation in the rheumatology clinic |
| title_sort | kimura disease a rare presentation in the rheumatology clinic |
| topic | angiolymphoid hyperplasia with eosinophilia eosinophilia immunoglobulin e kimura disease subcutaneous cheek swelling |
| url | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2020;volume=15;issue=4;spage=347;epage=353;aulast=Kumar |
| work_keys_str_mv | AT malaykumar kimuradiseaseararepresentationintherheumatologyclinic AT arunhegde kimuradiseaseararepresentationintherheumatologyclinic AT gunjandwivedi kimuradiseaseararepresentationintherheumatologyclinic AT prashantsengupta kimuradiseaseararepresentationintherheumatologyclinic AT kovilapuudaybhanu kimuradiseaseararepresentationintherheumatologyclinic |