Receptor-Mediated Endocytosis and Brain Delivery of Therapeutic Biologics
Transport of macromolecules across the blood-brain-barrier (BBB) requires both specific and nonspecific interactions between macromolecules and proteins/receptors expressed on the luminal and/or the abluminal surfaces of the brain capillary endothelial cells. Endocytosis and transcytosis play import...
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Main Authors: | Guangqing Xiao, Liang-Shang Gan |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
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Series: | International Journal of Cell Biology |
Online Access: | http://dx.doi.org/10.1155/2013/703545 |
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