Fever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document

The evaluation and workup of fever and the use of antibiotics to treat infections is part of daily practice in the surgical intensive care unit (ICU). Fever can be infectious or non-infectious; it is important to distinguish between the two entities wherever possible. The evidence is growing for sho...

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Main Authors: Deborah M Stein, Hee Soo Jung, Lisa M Kodadek, Bryce Robinson, Aussama Khalaf Nassar, Joseph Cuschieri, Michael Steven Farrell, Abhijit Pathak, Samuel Mandell, Jasmeet Paul, Rachel D Appelbaum, Eden Nohra, Thomas Carver, Jordan Michael Kirsch
Format: Article
Language:English
Published: BMJ Publishing Group 2024-04-01
Series:Trauma Surgery & Acute Care Open
Online Access:https://tsaco.bmj.com/content/9/1/e001303.full
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author Deborah M Stein
Hee Soo Jung
Lisa M Kodadek
Bryce Robinson
Aussama Khalaf Nassar
Joseph Cuschieri
Michael Steven Farrell
Abhijit Pathak
Samuel Mandell
Jasmeet Paul
Rachel D Appelbaum
Eden Nohra
Thomas Carver
Jordan Michael Kirsch
author_facet Deborah M Stein
Hee Soo Jung
Lisa M Kodadek
Bryce Robinson
Aussama Khalaf Nassar
Joseph Cuschieri
Michael Steven Farrell
Abhijit Pathak
Samuel Mandell
Jasmeet Paul
Rachel D Appelbaum
Eden Nohra
Thomas Carver
Jordan Michael Kirsch
author_sort Deborah M Stein
collection DOAJ
description The evaluation and workup of fever and the use of antibiotics to treat infections is part of daily practice in the surgical intensive care unit (ICU). Fever can be infectious or non-infectious; it is important to distinguish between the two entities wherever possible. The evidence is growing for shortening the duration of antibiotic treatment of common infections. The purpose of this clinical consensus document, created by the American Association for the Surgery of Trauma Critical Care Committee, is to synthesize the available evidence, and to provide practical recommendations. We discuss the evaluation of fever, the indications to obtain cultures including urine, blood, and respiratory specimens for diagnosis of infections, the use of procalcitonin, and the decision to initiate empiric antibiotics. We then describe the treatment of common infections, specifically ventilator-associated pneumonia, catheter-associated urinary infection, catheter-related bloodstream infection, bacteremia, surgical site infection, intra-abdominal infection, ventriculitis, and necrotizing soft tissue infection.
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series Trauma Surgery & Acute Care Open
spelling doaj-art-376e2860e59f494789f66754fe7caa5b2025-01-24T12:10:14ZengBMJ Publishing GroupTrauma Surgery & Acute Care Open2397-57762024-04-019110.1136/tsaco-2023-001303Fever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus documentDeborah M Stein0Hee Soo Jung1Lisa M Kodadek2Bryce Robinson3Aussama Khalaf Nassar4Joseph Cuschieri5Michael Steven Farrell6Abhijit Pathak7Samuel Mandell8Jasmeet Paul9Rachel D Appelbaum10Eden Nohra11Thomas Carver12Jordan Michael Kirsch13Surgery, Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, CA, United StatesDepartment of Surgery, University of Wisconsin Madison School of Medicine and Public Health, Madison, Wisconsin, USADepartment of Surgery, Yale University School of Medicine, New Haven, Connecticut, USADepartment of Surgery, Harborview Medical Center, Seattle, Washington, USADepartment of Surgery, Section of Acute Care Surgery, Stanford University, Stanford, California, USADepartment of Surgery, Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California, USADepartment of Surgery, Lehigh Valley Health Network, Allentown, Pennsylvania, USADepartment of Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania, USADepartment of Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas, USADepartment of Surgery, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USADepartment of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USADepartment of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USADepartment of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USAWashington University School of Medicine in Saint Louis, St Louis, Missouri, USAThe evaluation and workup of fever and the use of antibiotics to treat infections is part of daily practice in the surgical intensive care unit (ICU). Fever can be infectious or non-infectious; it is important to distinguish between the two entities wherever possible. The evidence is growing for shortening the duration of antibiotic treatment of common infections. The purpose of this clinical consensus document, created by the American Association for the Surgery of Trauma Critical Care Committee, is to synthesize the available evidence, and to provide practical recommendations. We discuss the evaluation of fever, the indications to obtain cultures including urine, blood, and respiratory specimens for diagnosis of infections, the use of procalcitonin, and the decision to initiate empiric antibiotics. We then describe the treatment of common infections, specifically ventilator-associated pneumonia, catheter-associated urinary infection, catheter-related bloodstream infection, bacteremia, surgical site infection, intra-abdominal infection, ventriculitis, and necrotizing soft tissue infection.https://tsaco.bmj.com/content/9/1/e001303.full
spellingShingle Deborah M Stein
Hee Soo Jung
Lisa M Kodadek
Bryce Robinson
Aussama Khalaf Nassar
Joseph Cuschieri
Michael Steven Farrell
Abhijit Pathak
Samuel Mandell
Jasmeet Paul
Rachel D Appelbaum
Eden Nohra
Thomas Carver
Jordan Michael Kirsch
Fever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document
Trauma Surgery & Acute Care Open
title Fever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document
title_full Fever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document
title_fullStr Fever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document
title_full_unstemmed Fever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document
title_short Fever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document
title_sort fever and infections in surgical intensive care an american association for the surgery of trauma critical care committee clinical consensus document
url https://tsaco.bmj.com/content/9/1/e001303.full
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