<i>Carthamus tinctorius</i> L. (Safflower) Flower Extract Attenuates Hepatic Injury and Steatosis in a Rat Model of Type 2 Diabetes Mellitus via Nrf2-Dependent Hypoglycemic, Antioxidant, and Hypolipidemic Effects

<i>Carthamus tinctorius</i> L. (Safflower) Flower Extract Attenuates Hepatic Injury and Steatosis in a Rat Model of Type 2 Diabetes Mellitus via Nrf2-Dependent Hypoglycemic, Antioxidant, and Hypolipidemic Effects

This study aimed to examine the hepatic and anti-steatotic protective effects of methanolic extract from <i>Carthamus tinctorius</i> (safflower) flowers (SFFE), using a rat model of type 2 diabetes mellitus (T2DM), and to examine the molecular mechanisms underlying these effects. Adult m...

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Bibliographic Details
Main Authors: Nuha Saad Alshareef, Sahar Abdulaziz AlSedairy, Laila Naif Al-Harbi, Ghedeir M. Alshammari, Mohammed Abdo Yahya
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Antioxidants
Subjects:
<i>Carthamus tinctorius</i>
safflower
liver
NAFLD
oxidative stress
Nrf2
Online Access:https://www.mdpi.com/2076-3921/13/9/1098
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