Regulation of Apoptosis in African Swine Fever Virus–Infected Macrophages
A number of viruses have evolved antiapoptotic mechanisms to promote infected-cell survival, either to ensure efficient productive viral replication or to promote long-term survival of virus-infected cells. Recent studies identified critical African swine fever virus genes involved in the complex re...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2002-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2002.214 |
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| _version_ | 1832555414225420288 |
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| author | Laslo Zsak John G. Neilan |
| author_facet | Laslo Zsak John G. Neilan |
| author_sort | Laslo Zsak |
| collection | DOAJ |
| description | A number of viruses have evolved antiapoptotic mechanisms to promote infected-cell survival, either to ensure efficient productive viral replication or to promote long-term survival of virus-infected cells. Recent studies identified critical African swine fever virus genes involved in the complex regulation of ASFV-host interactions. Here we review the present knowledge of the recently identified ASFV genes with special attention to those which affect viral virulence, host range, and pathogenesis by regulating viral-induced apoptotic mechanisms. |
| format | Article |
| id | doaj-art-3749bc23e69046119d50d7aa819b20f0 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2002-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-3749bc23e69046119d50d7aa819b20f02025-02-03T05:48:18ZengWileyThe Scientific World Journal1537-744X2002-01-0121186119510.1100/tsw.2002.214Regulation of Apoptosis in African Swine Fever Virus–Infected MacrophagesLaslo Zsak0John G. Neilan1Plum Island Animal Disease Center, USDA, ARS, P.O.Box 848, Greenport, NY 11944, USAPlum Island Animal Disease Center, USDA, ARS, P.O.Box 848, Greenport, NY 11944, USAA number of viruses have evolved antiapoptotic mechanisms to promote infected-cell survival, either to ensure efficient productive viral replication or to promote long-term survival of virus-infected cells. Recent studies identified critical African swine fever virus genes involved in the complex regulation of ASFV-host interactions. Here we review the present knowledge of the recently identified ASFV genes with special attention to those which affect viral virulence, host range, and pathogenesis by regulating viral-induced apoptotic mechanisms.http://dx.doi.org/10.1100/tsw.2002.214 |
| spellingShingle | Laslo Zsak John G. Neilan Regulation of Apoptosis in African Swine Fever Virus–Infected Macrophages The Scientific World Journal |
| title | Regulation of Apoptosis in African Swine Fever Virus–Infected Macrophages |
| title_full | Regulation of Apoptosis in African Swine Fever Virus–Infected Macrophages |
| title_fullStr | Regulation of Apoptosis in African Swine Fever Virus–Infected Macrophages |
| title_full_unstemmed | Regulation of Apoptosis in African Swine Fever Virus–Infected Macrophages |
| title_short | Regulation of Apoptosis in African Swine Fever Virus–Infected Macrophages |
| title_sort | regulation of apoptosis in african swine fever virus infected macrophages |
| url | http://dx.doi.org/10.1100/tsw.2002.214 |
| work_keys_str_mv | AT laslozsak regulationofapoptosisinafricanswinefevervirusinfectedmacrophages AT johngneilan regulationofapoptosisinafricanswinefevervirusinfectedmacrophages |