Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men

This study examined the association between consumption of alcoholic beverages and all-cause and cardiovascular disease (CVD) mortality in a cohort of men (n=31,367). In the Cox proportional hazards model adjusted for age, year of examination, body mass index (BMI), smoking, family history of CVD, a...

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Main Authors: Erin K. Howie, Xuemei Sui, Duck-chul Lee, Steven P. Hooker, James R. Hébert, Steven N. Blair
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Aging Research
Online Access:http://dx.doi.org/10.4061/2011/805062
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author Erin K. Howie
Xuemei Sui
Duck-chul Lee
Steven P. Hooker
James R. Hébert
Steven N. Blair
author_facet Erin K. Howie
Xuemei Sui
Duck-chul Lee
Steven P. Hooker
James R. Hébert
Steven N. Blair
author_sort Erin K. Howie
collection DOAJ
description This study examined the association between consumption of alcoholic beverages and all-cause and cardiovascular disease (CVD) mortality in a cohort of men (n=31,367). In the Cox proportional hazards model adjusted for age, year of examination, body mass index (BMI), smoking, family history of CVD, and aerobic fitness, there were no significant differences in risk of all-cause mortality across alcohol intake groups. Risk of CVD mortality was reduced 29% in quartile 1 (HR = 0.71, 95% confidence interval (CI): 0.53, 0.95) and 25% in quartile 2 (HR = 0.75, 95% CI: 0.58, 0.98). The amount of alcohol consumed to achieve this risk reduction was <6 drinks/week; less than the amount currently recommended. The addition of other potential confounders and effect modifiers including blood pressure, insulin sensitivity, lipid levels, and psychological variables did not affect the magnitude of association. Future research is needed to validate the current public health recommendations for alcohol consumption.
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spelling doaj-art-373a4db67ae84ff69383f2996404ed242025-02-03T01:23:41ZengWileyJournal of Aging Research2090-22122011-01-01201110.4061/2011/805062805062Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in MenErin K. Howie0Xuemei Sui1Duck-chul Lee2Steven P. Hooker3James R. Hébert4Steven N. Blair5Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC, USADepartment of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC, USADepartment of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC, USADepartment of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC, USACancer Prevention and Control Program and Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USADepartment of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC, USAThis study examined the association between consumption of alcoholic beverages and all-cause and cardiovascular disease (CVD) mortality in a cohort of men (n=31,367). In the Cox proportional hazards model adjusted for age, year of examination, body mass index (BMI), smoking, family history of CVD, and aerobic fitness, there were no significant differences in risk of all-cause mortality across alcohol intake groups. Risk of CVD mortality was reduced 29% in quartile 1 (HR = 0.71, 95% confidence interval (CI): 0.53, 0.95) and 25% in quartile 2 (HR = 0.75, 95% CI: 0.58, 0.98). The amount of alcohol consumed to achieve this risk reduction was <6 drinks/week; less than the amount currently recommended. The addition of other potential confounders and effect modifiers including blood pressure, insulin sensitivity, lipid levels, and psychological variables did not affect the magnitude of association. Future research is needed to validate the current public health recommendations for alcohol consumption.http://dx.doi.org/10.4061/2011/805062
spellingShingle Erin K. Howie
Xuemei Sui
Duck-chul Lee
Steven P. Hooker
James R. Hébert
Steven N. Blair
Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men
Journal of Aging Research
title Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men
title_full Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men
title_fullStr Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men
title_full_unstemmed Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men
title_short Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men
title_sort alcohol consumption and risk of all cause and cardiovascular disease mortality in men
url http://dx.doi.org/10.4061/2011/805062
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