Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men
This study examined the association between consumption of alcoholic beverages and all-cause and cardiovascular disease (CVD) mortality in a cohort of men (n=31,367). In the Cox proportional hazards model adjusted for age, year of examination, body mass index (BMI), smoking, family history of CVD, a...
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Language: | English |
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Wiley
2011-01-01
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Series: | Journal of Aging Research |
Online Access: | http://dx.doi.org/10.4061/2011/805062 |
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author | Erin K. Howie Xuemei Sui Duck-chul Lee Steven P. Hooker James R. Hébert Steven N. Blair |
author_facet | Erin K. Howie Xuemei Sui Duck-chul Lee Steven P. Hooker James R. Hébert Steven N. Blair |
author_sort | Erin K. Howie |
collection | DOAJ |
description | This study examined the association between consumption of alcoholic beverages and all-cause and cardiovascular disease (CVD) mortality in a cohort of men (n=31,367). In the Cox proportional hazards model adjusted for age, year of examination, body mass index (BMI), smoking, family history of CVD, and aerobic fitness, there were no significant differences in risk of all-cause mortality across alcohol intake groups. Risk of CVD mortality was reduced 29% in quartile 1 (HR = 0.71, 95% confidence interval (CI): 0.53, 0.95) and 25% in quartile 2 (HR = 0.75, 95% CI: 0.58, 0.98). The amount of alcohol consumed to achieve this risk reduction was <6 drinks/week; less than the amount currently recommended. The addition of other potential confounders and effect modifiers including blood pressure, insulin sensitivity, lipid levels, and psychological variables did not affect the magnitude of association. Future research is needed to validate the current public health recommendations for alcohol consumption. |
format | Article |
id | doaj-art-373a4db67ae84ff69383f2996404ed24 |
institution | Kabale University |
issn | 2090-2212 |
language | English |
publishDate | 2011-01-01 |
publisher | Wiley |
record_format | Article |
series | Journal of Aging Research |
spelling | doaj-art-373a4db67ae84ff69383f2996404ed242025-02-03T01:23:41ZengWileyJournal of Aging Research2090-22122011-01-01201110.4061/2011/805062805062Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in MenErin K. Howie0Xuemei Sui1Duck-chul Lee2Steven P. Hooker3James R. Hébert4Steven N. Blair5Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC, USADepartment of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC, USADepartment of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC, USADepartment of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC, USACancer Prevention and Control Program and Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USADepartment of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC, USAThis study examined the association between consumption of alcoholic beverages and all-cause and cardiovascular disease (CVD) mortality in a cohort of men (n=31,367). In the Cox proportional hazards model adjusted for age, year of examination, body mass index (BMI), smoking, family history of CVD, and aerobic fitness, there were no significant differences in risk of all-cause mortality across alcohol intake groups. Risk of CVD mortality was reduced 29% in quartile 1 (HR = 0.71, 95% confidence interval (CI): 0.53, 0.95) and 25% in quartile 2 (HR = 0.75, 95% CI: 0.58, 0.98). The amount of alcohol consumed to achieve this risk reduction was <6 drinks/week; less than the amount currently recommended. The addition of other potential confounders and effect modifiers including blood pressure, insulin sensitivity, lipid levels, and psychological variables did not affect the magnitude of association. Future research is needed to validate the current public health recommendations for alcohol consumption.http://dx.doi.org/10.4061/2011/805062 |
spellingShingle | Erin K. Howie Xuemei Sui Duck-chul Lee Steven P. Hooker James R. Hébert Steven N. Blair Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men Journal of Aging Research |
title | Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men |
title_full | Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men |
title_fullStr | Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men |
title_full_unstemmed | Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men |
title_short | Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men |
title_sort | alcohol consumption and risk of all cause and cardiovascular disease mortality in men |
url | http://dx.doi.org/10.4061/2011/805062 |
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