Noninvasive Monitoring of Pneumococcal Meningitis and Evaluation of Treatment Efficacy in an Experimental Mouse Model

Noninvasive real-time in vivo bioluminescent imaging was used to assess the spread of Streptococcus pneumoniae throughout the spinal cord and brain during the acute stages of bacterial meningitis. A mouse model was established by lumbar (LP) or intracisternal (IC) injection of bioluminescent S. pneu...

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Bibliographic Details
Main Authors: Jagath L. Kadurugamuwa, Kshitij Modi, Jun Yu, Kevin P. Francis, Carlos Orihuela, Elaine Tuomanen, Anthony F. Purchio, Pamela R. Contag
Format: Article
Language:English
Published: SAGE Publishing 2005-04-01
Series:Molecular Imaging
Online Access:https://doi.org/10.1162/15353500200505106
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