Best Evidence Summary for the Improvement and Management of Disorders of Consciousness in Patients With Severe Brain Injury
ABSTRACT Background and Purpose The treatment effect of consciousness after brain injury is currently uncertain. Thus, this study aimed to retrieve the evidence from neurologists around the world on the management of consciousness disorders in patients with severe brain injury and evaluate and summa...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Brain and Behavior |
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| Online Access: | https://doi.org/10.1002/brb3.70260 |
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| author | Miaoyuan Lin Qiongna Lu Sheng Yu Wenjuan Lin |
| author_facet | Miaoyuan Lin Qiongna Lu Sheng Yu Wenjuan Lin |
| author_sort | Miaoyuan Lin |
| collection | DOAJ |
| description | ABSTRACT Background and Purpose The treatment effect of consciousness after brain injury is currently uncertain. Thus, this study aimed to retrieve the evidence from neurologists around the world on the management of consciousness disorders in patients with severe brain injury and evaluate and summarize the evidence, providing the guidance on the related management for clinicians. Methods Following the evidence summary report standard of Fudan University Center for Evidence‐Based Nursing, clinical guidelines, expert consensuses, systematic reviews, and evidence summaries were systematically retrieved from UpToDate; BMJ Best Practice; Guidelines International Network; the Cochrane Library; Embase; PubMed; Sinomed; Web of Science; CNKI; WanFang database; American Academy of Neurology (AAN); American Congress of Rehabilitation Medicine (ACRM); European Academy of Neurology; and National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR). The publishing timeline for articles was limited from January 2017 to January 2024. Results Fourteen articles were finally identified. The 26 best pieces of evidence were recommended by inducting and integrating the evidence from these articles, covering the following seven aspects: consciousness assessment, multidisciplinary team, intervention in facilitating arousal, sensory stimulation programs, drug administration, rehabilitation program, and prevention of complications. Conclusion This study summarized the evidence of consciousness management in patients with brain injury, providing guidance for clinicians to develop and apply those interventions to improve the patient's clinical outcomes and quality of life. In addition, relevant factors such as the clinical environment and cooperation with the patient's family members should be evaluated and adjusted before applying such evidence. Future studies should focus on more targeted randomized clinical trials. |
| format | Article |
| id | doaj-art-3716b68a01ce4d3aa60a142cb517ce6a |
| institution | Kabale University |
| issn | 2162-3279 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Brain and Behavior |
| spelling | doaj-art-3716b68a01ce4d3aa60a142cb517ce6a2025-01-29T13:36:39ZengWileyBrain and Behavior2162-32792025-01-01151n/an/a10.1002/brb3.70260Best Evidence Summary for the Improvement and Management of Disorders of Consciousness in Patients With Severe Brain InjuryMiaoyuan Lin0Qiongna Lu1Sheng Yu2Wenjuan Lin3Department of Neurosurgery Shenzhen Nanshan People's Hospital Shenzhen Guangdong People's Republic of ChinaSchool of Health Guangzhou Vocational and Technical University of Science and Technology Guangzhou Guangdong People's Republic of ChinaDepartment of Neurosurgery Shenzhen Nanshan People's Hospital Shenzhen Guangdong People's Republic of ChinaDepartment of Neurosurgery Shenzhen Nanshan People's Hospital Shenzhen Guangdong People's Republic of ChinaABSTRACT Background and Purpose The treatment effect of consciousness after brain injury is currently uncertain. Thus, this study aimed to retrieve the evidence from neurologists around the world on the management of consciousness disorders in patients with severe brain injury and evaluate and summarize the evidence, providing the guidance on the related management for clinicians. Methods Following the evidence summary report standard of Fudan University Center for Evidence‐Based Nursing, clinical guidelines, expert consensuses, systematic reviews, and evidence summaries were systematically retrieved from UpToDate; BMJ Best Practice; Guidelines International Network; the Cochrane Library; Embase; PubMed; Sinomed; Web of Science; CNKI; WanFang database; American Academy of Neurology (AAN); American Congress of Rehabilitation Medicine (ACRM); European Academy of Neurology; and National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR). The publishing timeline for articles was limited from January 2017 to January 2024. Results Fourteen articles were finally identified. The 26 best pieces of evidence were recommended by inducting and integrating the evidence from these articles, covering the following seven aspects: consciousness assessment, multidisciplinary team, intervention in facilitating arousal, sensory stimulation programs, drug administration, rehabilitation program, and prevention of complications. Conclusion This study summarized the evidence of consciousness management in patients with brain injury, providing guidance for clinicians to develop and apply those interventions to improve the patient's clinical outcomes and quality of life. In addition, relevant factors such as the clinical environment and cooperation with the patient's family members should be evaluated and adjusted before applying such evidence. Future studies should focus on more targeted randomized clinical trials.https://doi.org/10.1002/brb3.70260awarenessbrain injurydisorders of consciousnessevidence summary |
| spellingShingle | Miaoyuan Lin Qiongna Lu Sheng Yu Wenjuan Lin Best Evidence Summary for the Improvement and Management of Disorders of Consciousness in Patients With Severe Brain Injury Brain and Behavior awareness brain injury disorders of consciousness evidence summary |
| title | Best Evidence Summary for the Improvement and Management of Disorders of Consciousness in Patients With Severe Brain Injury |
| title_full | Best Evidence Summary for the Improvement and Management of Disorders of Consciousness in Patients With Severe Brain Injury |
| title_fullStr | Best Evidence Summary for the Improvement and Management of Disorders of Consciousness in Patients With Severe Brain Injury |
| title_full_unstemmed | Best Evidence Summary for the Improvement and Management of Disorders of Consciousness in Patients With Severe Brain Injury |
| title_short | Best Evidence Summary for the Improvement and Management of Disorders of Consciousness in Patients With Severe Brain Injury |
| title_sort | best evidence summary for the improvement and management of disorders of consciousness in patients with severe brain injury |
| topic | awareness brain injury disorders of consciousness evidence summary |
| url | https://doi.org/10.1002/brb3.70260 |
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