Challenging Diagnosis of Addison’s Disease Presenting with Adrenal Crisis
Primary adrenal insufficiency, also known as Addison’s disease, is a rare but potentially fatal condition resulting from the failure of the adrenal cortex to produce glucocorticoid and/or mineralocorticoid hormones. Unfortunately, the clinical manifestation of primary adrenal insufficiency is not sp...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2021/7137950 |
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| author | Ni Wayan Wina Dharmesti Made Ratna Saraswati Ketut Suastika Wira Gotera I Made Pande Dwipayana |
| author_facet | Ni Wayan Wina Dharmesti Made Ratna Saraswati Ketut Suastika Wira Gotera I Made Pande Dwipayana |
| author_sort | Ni Wayan Wina Dharmesti |
| collection | DOAJ |
| description | Primary adrenal insufficiency, also known as Addison’s disease, is a rare but potentially fatal condition resulting from the failure of the adrenal cortex to produce glucocorticoid and/or mineralocorticoid hormones. Unfortunately, the clinical manifestation of primary adrenal insufficiency is not specific and often progresses insidiously, resulting in late diagnosis, or in severe cases, life-threatening circulatory collapse. Adrenal insufficiency should be considered in patients with unexplained vascular collapse. We report the case of a woman who presented to the emergency ward with unexplainable shock that was later diagnosed as adrenal crisis due to Addison’s disease. The presence of hyperpigmentation in patients with rapid progression of adrenal insufficiency suggests the diagnosis of Addison’s disease presenting with adrenal crisis. |
| format | Article |
| id | doaj-art-3707a0d840ce46ac9527fd2f2ab615cc |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-3707a0d840ce46ac9527fd2f2ab615cc2025-02-03T01:08:58ZengWileyCase Reports in Endocrinology2090-65012090-651X2021-01-01202110.1155/2021/71379507137950Challenging Diagnosis of Addison’s Disease Presenting with Adrenal CrisisNi Wayan Wina Dharmesti0Made Ratna Saraswati1Ketut Suastika2Wira Gotera3I Made Pande Dwipayana4Resident: Internal Medicine Department, Faculty of Medicine Udayana University, Sanglah Hospital, Denpasar, Bali, IndonesiaEndocrine and Metabolism Division, Internal Medicine Department, Faculty of Medicine Udayana University, Sanglah Hospital, Denpasar, Bali, IndonesiaEndocrine and Metabolism Division, Internal Medicine Department, Faculty of Medicine Udayana University, Sanglah Hospital, Denpasar, Bali, IndonesiaEndocrine and Metabolism Division, Internal Medicine Department, Faculty of Medicine Udayana University, Sanglah Hospital, Denpasar, Bali, IndonesiaEndocrine and Metabolism Division, Internal Medicine Department, Faculty of Medicine Udayana University, Sanglah Hospital, Denpasar, Bali, IndonesiaPrimary adrenal insufficiency, also known as Addison’s disease, is a rare but potentially fatal condition resulting from the failure of the adrenal cortex to produce glucocorticoid and/or mineralocorticoid hormones. Unfortunately, the clinical manifestation of primary adrenal insufficiency is not specific and often progresses insidiously, resulting in late diagnosis, or in severe cases, life-threatening circulatory collapse. Adrenal insufficiency should be considered in patients with unexplained vascular collapse. We report the case of a woman who presented to the emergency ward with unexplainable shock that was later diagnosed as adrenal crisis due to Addison’s disease. The presence of hyperpigmentation in patients with rapid progression of adrenal insufficiency suggests the diagnosis of Addison’s disease presenting with adrenal crisis.http://dx.doi.org/10.1155/2021/7137950 |
| spellingShingle | Ni Wayan Wina Dharmesti Made Ratna Saraswati Ketut Suastika Wira Gotera I Made Pande Dwipayana Challenging Diagnosis of Addison’s Disease Presenting with Adrenal Crisis Case Reports in Endocrinology |
| title | Challenging Diagnosis of Addison’s Disease Presenting with Adrenal Crisis |
| title_full | Challenging Diagnosis of Addison’s Disease Presenting with Adrenal Crisis |
| title_fullStr | Challenging Diagnosis of Addison’s Disease Presenting with Adrenal Crisis |
| title_full_unstemmed | Challenging Diagnosis of Addison’s Disease Presenting with Adrenal Crisis |
| title_short | Challenging Diagnosis of Addison’s Disease Presenting with Adrenal Crisis |
| title_sort | challenging diagnosis of addison s disease presenting with adrenal crisis |
| url | http://dx.doi.org/10.1155/2021/7137950 |
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