Biosynthetic mesh in hernia repair: A systematic review and meta-analysis
INTRODUCTION: Biosynthetic mesh is the latest class of hernia mesh. It is a slowly absorbable synthetic mesh and promises to reduce hernia recurrence and other complications, such as mesh infection, erosion, adhesions, and chronic pain. This study aims to systematically review the literature on bios...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-04-01
|
| Series: | International Journal of Abdominal Wall and Hernia Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.4103/ijawhs.ijawhs_99_23 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832586499056467968 |
|---|---|
| author | Iyad S. Al-Bustami Thomas Clements Dalya Ferguson Alamin Harmouch Oscar A. Olavarria Julie L. Holihan |
| author_facet | Iyad S. Al-Bustami Thomas Clements Dalya Ferguson Alamin Harmouch Oscar A. Olavarria Julie L. Holihan |
| author_sort | Iyad S. Al-Bustami |
| collection | DOAJ |
| description | INTRODUCTION: Biosynthetic mesh is the latest class of hernia mesh. It is a slowly absorbable synthetic mesh and promises to reduce hernia recurrence and other complications, such as mesh infection, erosion, adhesions, and chronic pain. This study aims to systematically review the literature on biosynthetic mesh in ventral hernia repair. MATERIALS AND METHODS: A search of MEDLINE, Cochrane, and Scopus databases was conducted to identify studies using biosynthetic mesh in ventral hernia repair. The Strengthening the Reporting of Observational Studies in Epidemiology checklist was utilized to assess study quality. The primary outcome assessed was hernia recurrence. Secondary outcomes included surgical site infection (SSI), surgical site occurrence (SSO), and reoperation. Heterogeneity was assessed using I2, and a random effects model was used for meta-analysis. RESULTS: Thirty-six studies were included, all of which were observational. Follow-up ranged from 1 to 98 months postoperative. Hernia recurrence was reported in 35 studies, yielding a pooled recurrence rate of 10% (95% CI, 8%–12%). SSI was reported in 30 studies, with a pooled recurrence rate of 8% (95% CI, 6%–11%). SSO was reported in 29 studies and ranged from 1% to 56%. Reoperation was reported in 26 studies, with a pooled reoperation rate of 9% (95% CI, 6%–11%). CONCLUSIONS: This review underscores the paucity of high-quality studies on biosynthetic mesh. While observational studies of hernia repair using biosynthetic mesh suggest it may be safe with acceptable outcomes, high-quality trials with long-term follow-up are necessary before widespread implementation of these mesh types. |
| format | Article |
| id | doaj-art-3704dabc760349c694d15998dd5e1f7f |
| institution | Kabale University |
| issn | 2589-8736 2589-8078 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Abdominal Wall and Hernia Surgery |
| spelling | doaj-art-3704dabc760349c694d15998dd5e1f7f2025-01-25T10:01:22ZengWolters Kluwer Medknow PublicationsInternational Journal of Abdominal Wall and Hernia Surgery2589-87362589-80782024-04-0172556610.4103/ijawhs.ijawhs_99_23Biosynthetic mesh in hernia repair: A systematic review and meta-analysisIyad S. Al-BustamiThomas ClementsDalya FergusonAlamin HarmouchOscar A. OlavarriaJulie L. HolihanINTRODUCTION: Biosynthetic mesh is the latest class of hernia mesh. It is a slowly absorbable synthetic mesh and promises to reduce hernia recurrence and other complications, such as mesh infection, erosion, adhesions, and chronic pain. This study aims to systematically review the literature on biosynthetic mesh in ventral hernia repair. MATERIALS AND METHODS: A search of MEDLINE, Cochrane, and Scopus databases was conducted to identify studies using biosynthetic mesh in ventral hernia repair. The Strengthening the Reporting of Observational Studies in Epidemiology checklist was utilized to assess study quality. The primary outcome assessed was hernia recurrence. Secondary outcomes included surgical site infection (SSI), surgical site occurrence (SSO), and reoperation. Heterogeneity was assessed using I2, and a random effects model was used for meta-analysis. RESULTS: Thirty-six studies were included, all of which were observational. Follow-up ranged from 1 to 98 months postoperative. Hernia recurrence was reported in 35 studies, yielding a pooled recurrence rate of 10% (95% CI, 8%–12%). SSI was reported in 30 studies, with a pooled recurrence rate of 8% (95% CI, 6%–11%). SSO was reported in 29 studies and ranged from 1% to 56%. Reoperation was reported in 26 studies, with a pooled reoperation rate of 9% (95% CI, 6%–11%). CONCLUSIONS: This review underscores the paucity of high-quality studies on biosynthetic mesh. While observational studies of hernia repair using biosynthetic mesh suggest it may be safe with acceptable outcomes, high-quality trials with long-term follow-up are necessary before widespread implementation of these mesh types.https://doi.org/10.4103/ijawhs.ijawhs_99_23bio-abiosyntheticherniameshphasixpoly-4-hydroxybutyrate |
| spellingShingle | Iyad S. Al-Bustami Thomas Clements Dalya Ferguson Alamin Harmouch Oscar A. Olavarria Julie L. Holihan Biosynthetic mesh in hernia repair: A systematic review and meta-analysis International Journal of Abdominal Wall and Hernia Surgery bio-a biosynthetic hernia mesh phasix poly-4-hydroxybutyrate |
| title | Biosynthetic mesh in hernia repair: A systematic review and meta-analysis |
| title_full | Biosynthetic mesh in hernia repair: A systematic review and meta-analysis |
| title_fullStr | Biosynthetic mesh in hernia repair: A systematic review and meta-analysis |
| title_full_unstemmed | Biosynthetic mesh in hernia repair: A systematic review and meta-analysis |
| title_short | Biosynthetic mesh in hernia repair: A systematic review and meta-analysis |
| title_sort | biosynthetic mesh in hernia repair a systematic review and meta analysis |
| topic | bio-a biosynthetic hernia mesh phasix poly-4-hydroxybutyrate |
| url | https://doi.org/10.4103/ijawhs.ijawhs_99_23 |
| work_keys_str_mv | AT iyadsalbustami biosyntheticmeshinherniarepairasystematicreviewandmetaanalysis AT thomasclements biosyntheticmeshinherniarepairasystematicreviewandmetaanalysis AT dalyaferguson biosyntheticmeshinherniarepairasystematicreviewandmetaanalysis AT alaminharmouch biosyntheticmeshinherniarepairasystematicreviewandmetaanalysis AT oscaraolavarria biosyntheticmeshinherniarepairasystematicreviewandmetaanalysis AT julielholihan biosyntheticmeshinherniarepairasystematicreviewandmetaanalysis |