Future perspectives for PDE5 inhibitors bridging the gap between cardiovascular health and psychological status
Abstract The serendipitous discovery that inhibiting type 5 phosphodiesterase (PDE5) using sildenafil, a potent PDE5 inhibitor (PDE5i) initially developed for cardioprotection, introduced the possibility of orally managing erectile dysfunction (ED) led to an increase in research data, which are curr...
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Main Authors: | Andrea Sansone, Eugenia Guida, Susanna Dolci, Valeria Frangione, Amanda Asso, Gilberto Bellia, Emmanuele A. Jannini |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Basic and Clinical Andrology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12610-024-00245-y |
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