Chronic Heroin Dependence Leading to Adrenal Insufficiency
Opioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on the endocrine system is poorly understood and...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2014/461816 |
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| _version_ | 1832567026350030848 |
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| author | Gautam Das |
| author_facet | Gautam Das |
| author_sort | Gautam Das |
| collection | DOAJ |
| description | Opioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on the endocrine system is poorly understood and often underestimated. We describe a patient who developed severe suppression of the hypothalamic-pituitary adrenal (HPA) axis leading to secondary adrenal insufficiency due to long standing abuse of opioids. |
| format | Article |
| id | doaj-art-36ac1d47f38143a0a81040c86cb53090 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-36ac1d47f38143a0a81040c86cb530902025-02-03T01:02:27ZengWileyCase Reports in Endocrinology2090-65012090-651X2014-01-01201410.1155/2014/461816461816Chronic Heroin Dependence Leading to Adrenal InsufficiencyGautam Das0Department of Diabetes and Endocrinology, Prince Charles Hospital, Cwm Taf NHS Trust, Gurnos, Merthyr Tydfil, CF47 9DT, UKOpioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on the endocrine system is poorly understood and often underestimated. We describe a patient who developed severe suppression of the hypothalamic-pituitary adrenal (HPA) axis leading to secondary adrenal insufficiency due to long standing abuse of opioids.http://dx.doi.org/10.1155/2014/461816 |
| spellingShingle | Gautam Das Chronic Heroin Dependence Leading to Adrenal Insufficiency Case Reports in Endocrinology |
| title | Chronic Heroin Dependence Leading to Adrenal Insufficiency |
| title_full | Chronic Heroin Dependence Leading to Adrenal Insufficiency |
| title_fullStr | Chronic Heroin Dependence Leading to Adrenal Insufficiency |
| title_full_unstemmed | Chronic Heroin Dependence Leading to Adrenal Insufficiency |
| title_short | Chronic Heroin Dependence Leading to Adrenal Insufficiency |
| title_sort | chronic heroin dependence leading to adrenal insufficiency |
| url | http://dx.doi.org/10.1155/2014/461816 |
| work_keys_str_mv | AT gautamdas chronicheroindependenceleadingtoadrenalinsufficiency |