Synthesis and Antimicrobial Activity of Pyrimidine Salts with Chloranilic and Picric Acids
Pyrimidine salts such as 2-methyl-5-nitro-phenyl-(4-pyridin-3-yl-pyrimidin-2-yl)-amine (1) and 4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-yl-amino)-phenyl-amine (2) with chloranilic and picric acids were synthesized, and their in vitro antibacterial and antifungal activities were evaluated. The synthesi...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/727182 |
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| author | C. Mallikarjunaswamy D. G. Bhadregowda L. Mallesha |
| author_facet | C. Mallikarjunaswamy D. G. Bhadregowda L. Mallesha |
| author_sort | C. Mallikarjunaswamy |
| collection | DOAJ |
| description | Pyrimidine salts such as 2-methyl-5-nitro-phenyl-(4-pyridin-3-yl-pyrimidin-2-yl)-amine (1) and 4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-yl-amino)-phenyl-amine (2) with chloranilic and picric acids were synthesized, and their in vitro antibacterial and antifungal activities were evaluated. The synthesized compounds were characterized by elemental analyses, UV-visible, FT-IR, and 1H NMR spectral studies. Compound 2a exhibited good inhibition towards antimicrobial activity compared to the other compounds. |
| format | Article |
| id | doaj-art-36612d3dc38d400c8d89013801690bdb |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-36612d3dc38d400c8d89013801690bdb2025-02-03T01:03:31ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/727182727182Synthesis and Antimicrobial Activity of Pyrimidine Salts with Chloranilic and Picric AcidsC. Mallikarjunaswamy0D. G. Bhadregowda1L. Mallesha2Department of Chemistry, Yuvaraja's College, University of Mysore, Mysore 570005, IndiaDepartment of Chemistry, Yuvaraja's College, University of Mysore, Mysore 570005, IndiaPG Department of Studies in Chemistry, JSS College of Arts, Commerce and Science, Ooty Road, Mysore 570025, IndiaPyrimidine salts such as 2-methyl-5-nitro-phenyl-(4-pyridin-3-yl-pyrimidin-2-yl)-amine (1) and 4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-yl-amino)-phenyl-amine (2) with chloranilic and picric acids were synthesized, and their in vitro antibacterial and antifungal activities were evaluated. The synthesized compounds were characterized by elemental analyses, UV-visible, FT-IR, and 1H NMR spectral studies. Compound 2a exhibited good inhibition towards antimicrobial activity compared to the other compounds.http://dx.doi.org/10.1155/2013/727182 |
| spellingShingle | C. Mallikarjunaswamy D. G. Bhadregowda L. Mallesha Synthesis and Antimicrobial Activity of Pyrimidine Salts with Chloranilic and Picric Acids Journal of Chemistry |
| title | Synthesis and Antimicrobial Activity of Pyrimidine Salts with Chloranilic and Picric Acids |
| title_full | Synthesis and Antimicrobial Activity of Pyrimidine Salts with Chloranilic and Picric Acids |
| title_fullStr | Synthesis and Antimicrobial Activity of Pyrimidine Salts with Chloranilic and Picric Acids |
| title_full_unstemmed | Synthesis and Antimicrobial Activity of Pyrimidine Salts with Chloranilic and Picric Acids |
| title_short | Synthesis and Antimicrobial Activity of Pyrimidine Salts with Chloranilic and Picric Acids |
| title_sort | synthesis and antimicrobial activity of pyrimidine salts with chloranilic and picric acids |
| url | http://dx.doi.org/10.1155/2013/727182 |
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