Neuroborreliosis mimicking demyelinating disease of the central nervous system: case reports
We present two patients with neuroborreliosis initially considered as demyelinating disease of the central nervous system. The first patient developed facial numbness on the right side, diplopia and dizziness that lasted about half a year. Magnetic resonance imaging of the brain showed confluent hy...
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| Format: | Article |
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Vilnius University Press
2018-09-01
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| Series: | Neurologijos seminarai |
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| Online Access: | https://www.journals.vu.lt/neurologijos_seminarai/article/view/27830 |
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| author | N. Giedraitienė A. Lisinskaitė A. Klimašauskienė |
| author_facet | N. Giedraitienė A. Lisinskaitė A. Klimašauskienė |
| author_sort | N. Giedraitienė |
| collection | DOAJ |
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We present two patients with neuroborreliosis initially considered as demyelinating disease of the central nervous system. The first patient developed facial numbness on the right side, diplopia and dizziness that lasted about half a year. Magnetic resonance imaging of the brain showed confluent hyperintense lesions and visual evoked potentials revealed prolonged latencies of the P wave. The second patient developed weakness, numbness and pain in the left hand that lasted several weeks. Magnetic resonance imaging of the cervical spine demonstrated hyperintense lesions commonly found in multiple sclerosis. In both cases, positive serology for Borrelia burgdorferi was an indicator of past infection. However, the cerebrospinal fluid analysis showed proteinorrhachia and lymphocytic pleocytosis and the presence of specific IgM and IgG antibodies in the cerebrospinal fluid confirmed the diagnosis of neuroborreliosis. The clinical symptoms, abnormal cytological, biochemical and immunological cerebrospinal fluid findings in combination with good response to antibiotic therapy confirmed the diagnosis of neuroborreliosis in our patients.
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| format | Article |
| id | doaj-art-363782d8c05c4b67903715213aeb989b |
| institution | Kabale University |
| issn | 1392-3064 2424-5917 |
| language | English |
| publishDate | 2018-09-01 |
| publisher | Vilnius University Press |
| record_format | Article |
| series | Neurologijos seminarai |
| spelling | doaj-art-363782d8c05c4b67903715213aeb989b2025-01-20T18:23:10ZengVilnius University PressNeurologijos seminarai1392-30642424-59172018-09-01223(77)10.29014/ns.2018.27Neuroborreliosis mimicking demyelinating disease of the central nervous system: case reportsN. Giedraitienė 0A. Lisinskaitė 1A. Klimašauskienė 2Vilnius University, LithuaniaVilnius University, LithuaniaVilnius University, Lithuania We present two patients with neuroborreliosis initially considered as demyelinating disease of the central nervous system. The first patient developed facial numbness on the right side, diplopia and dizziness that lasted about half a year. Magnetic resonance imaging of the brain showed confluent hyperintense lesions and visual evoked potentials revealed prolonged latencies of the P wave. The second patient developed weakness, numbness and pain in the left hand that lasted several weeks. Magnetic resonance imaging of the cervical spine demonstrated hyperintense lesions commonly found in multiple sclerosis. In both cases, positive serology for Borrelia burgdorferi was an indicator of past infection. However, the cerebrospinal fluid analysis showed proteinorrhachia and lymphocytic pleocytosis and the presence of specific IgM and IgG antibodies in the cerebrospinal fluid confirmed the diagnosis of neuroborreliosis. The clinical symptoms, abnormal cytological, biochemical and immunological cerebrospinal fluid findings in combination with good response to antibiotic therapy confirmed the diagnosis of neuroborreliosis in our patients. https://www.journals.vu.lt/neurologijos_seminarai/article/view/27830neuroborreliosisLyme diseasemultiple sclerosisdemyelinating disease of the central nervous system |
| spellingShingle | N. Giedraitienė A. Lisinskaitė A. Klimašauskienė Neuroborreliosis mimicking demyelinating disease of the central nervous system: case reports Neurologijos seminarai neuroborreliosis Lyme disease multiple sclerosis demyelinating disease of the central nervous system |
| title | Neuroborreliosis mimicking demyelinating disease of the central nervous system: case reports |
| title_full | Neuroborreliosis mimicking demyelinating disease of the central nervous system: case reports |
| title_fullStr | Neuroborreliosis mimicking demyelinating disease of the central nervous system: case reports |
| title_full_unstemmed | Neuroborreliosis mimicking demyelinating disease of the central nervous system: case reports |
| title_short | Neuroborreliosis mimicking demyelinating disease of the central nervous system: case reports |
| title_sort | neuroborreliosis mimicking demyelinating disease of the central nervous system case reports |
| topic | neuroborreliosis Lyme disease multiple sclerosis demyelinating disease of the central nervous system |
| url | https://www.journals.vu.lt/neurologijos_seminarai/article/view/27830 |
| work_keys_str_mv | AT ngiedraitiene neuroborreliosismimickingdemyelinatingdiseaseofthecentralnervoussystemcasereports AT alisinskaite neuroborreliosismimickingdemyelinatingdiseaseofthecentralnervoussystemcasereports AT aklimasauskiene neuroborreliosismimickingdemyelinatingdiseaseofthecentralnervoussystemcasereports |