Targeting Soluble Amyloid Oligomers in Alzheimer’s Disease: A Hypothetical Model Study Comparing Intrathecal Pseudodelivery of mAbs Against Intravenous Administration
Background/Objective: Neurotoxic soluble amyloid-β (Aβ) oligomers are key drivers of Alzheimer’s pathology, with evidence suggesting that early targeting of these soluble forms may slow disease progression. Traditional intravenous (IV) monoclonal antibodies (mAbs) face challenges, including limited...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-01-01
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| Series: | Diseases |
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| Online Access: | https://www.mdpi.com/2079-9721/13/1/17 |
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