Current trends and research advances on the application of TiO2 nanoparticles in dentistry: How far are we from clinical translation?
The great potential of nanotechnology-based knowledge during the past decade has shown great potential to elevate human living standards and enhance healthcare conditions through diagnosing, preventing, and treating different diseases. Among abundant nanoparticles (NPs), inorganic NPs feature distin...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844025005493 |
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| author | Hossein Mohammadi Hedaiat Moradpoor Salmia Beddu Hamid Reza Mozaffari Roohollah Sharifi Razieh Rezaei Nima Fallahnia Mona Ebadi Saiful Amri Mazlan Mohsen Safaei |
| author_facet | Hossein Mohammadi Hedaiat Moradpoor Salmia Beddu Hamid Reza Mozaffari Roohollah Sharifi Razieh Rezaei Nima Fallahnia Mona Ebadi Saiful Amri Mazlan Mohsen Safaei |
| author_sort | Hossein Mohammadi |
| collection | DOAJ |
| description | The great potential of nanotechnology-based knowledge during the past decade has shown great potential to elevate human living standards and enhance healthcare conditions through diagnosing, preventing, and treating different diseases. Among abundant nanoparticles (NPs), inorganic NPs feature distinctive biological and physicochemical properties compared to their conventional counterparts which do not endow. TiO2 NPs possess excellent properties including low-cast, antibacterial properties, biocompatibility, and physicochemical stability. The present review highlights and discusses the current trends in applying TiO2 NPs in dentistry ranging from TiO2-based nanocomposite in endodontics, orthodontics, and biofilm prevention. Moreover, the potential of TiO2 NPs in developing new photodynamic therapy and the next generation of oral care products is outlined. In the end, the clinical translation of TiO2-based dental materials is brought to the forefront which is impetus and of great importance to developing inorganic NP-based dental materials. |
| format | Article |
| id | doaj-art-362d9ebe7caf4ed49dbbaea6e317ac5a |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-362d9ebe7caf4ed49dbbaea6e317ac5a2025-02-05T04:32:16ZengElsevierHeliyon2405-84402025-02-01113e42169Current trends and research advances on the application of TiO2 nanoparticles in dentistry: How far are we from clinical translation?Hossein Mohammadi0Hedaiat Moradpoor1Salmia Beddu2Hamid Reza Mozaffari3Roohollah Sharifi4Razieh Rezaei5Nima Fallahnia6Mona Ebadi7Saiful Amri Mazlan8Mohsen Safaei9School of Materials and Mineral Resources Engineering, Universiti Sains Malaysia, Engineering Campus, Nibong Tebal, 14300, Penang, Malaysia; Institute of Energy Infrastructure (IEI), Department of Civil Engineering, College of Engineering, Universiti Tenaga Nasional, Jalan IKRAM-UNITEN, 43000, Kajang, Selangor, MalaysiaDepartment of Prosthodontics, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, IranInstitute of Energy Infrastructure (IEI), Department of Civil Engineering, College of Engineering, Universiti Tenaga Nasional, Jalan IKRAM-UNITEN, 43000, Kajang, Selangor, MalaysiaDepartment of Oral and Maxillofacial Medicine, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, IranDepartment of Endodontics, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, IranAdvanced Dental Science and Technology Research Center, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, IranStudents Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran; Division of Dental Biomaterials, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, IranEngineering Materials and Structures (eMast) Ikohza, Malaysia–Japan International Institute of Technology (MJIIT), Universiti Teknologi Malaysia, Kuala Lumpur 54100, MalaysiaEngineering Materials and Structures (eMast) Ikohza, Malaysia–Japan International Institute of Technology (MJIIT), Universiti Teknologi Malaysia, Kuala Lumpur 54100, Malaysia; Corresponding author.Advanced Dental Science and Technology Research Center, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran; Division of Dental Biomaterials, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran; Corresponding author. Advanced Dental Science and Technology Research Center, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran.The great potential of nanotechnology-based knowledge during the past decade has shown great potential to elevate human living standards and enhance healthcare conditions through diagnosing, preventing, and treating different diseases. Among abundant nanoparticles (NPs), inorganic NPs feature distinctive biological and physicochemical properties compared to their conventional counterparts which do not endow. TiO2 NPs possess excellent properties including low-cast, antibacterial properties, biocompatibility, and physicochemical stability. The present review highlights and discusses the current trends in applying TiO2 NPs in dentistry ranging from TiO2-based nanocomposite in endodontics, orthodontics, and biofilm prevention. Moreover, the potential of TiO2 NPs in developing new photodynamic therapy and the next generation of oral care products is outlined. In the end, the clinical translation of TiO2-based dental materials is brought to the forefront which is impetus and of great importance to developing inorganic NP-based dental materials.http://www.sciencedirect.com/science/article/pii/S2405844025005493Inorganic nanoparticlesTitanium dioxideCompositeAntibacterial propertiesMechanical propertiesGlossiness |
| spellingShingle | Hossein Mohammadi Hedaiat Moradpoor Salmia Beddu Hamid Reza Mozaffari Roohollah Sharifi Razieh Rezaei Nima Fallahnia Mona Ebadi Saiful Amri Mazlan Mohsen Safaei Current trends and research advances on the application of TiO2 nanoparticles in dentistry: How far are we from clinical translation? Heliyon Inorganic nanoparticles Titanium dioxide Composite Antibacterial properties Mechanical properties Glossiness |
| title | Current trends and research advances on the application of TiO2 nanoparticles in dentistry: How far are we from clinical translation? |
| title_full | Current trends and research advances on the application of TiO2 nanoparticles in dentistry: How far are we from clinical translation? |
| title_fullStr | Current trends and research advances on the application of TiO2 nanoparticles in dentistry: How far are we from clinical translation? |
| title_full_unstemmed | Current trends and research advances on the application of TiO2 nanoparticles in dentistry: How far are we from clinical translation? |
| title_short | Current trends and research advances on the application of TiO2 nanoparticles in dentistry: How far are we from clinical translation? |
| title_sort | current trends and research advances on the application of tio2 nanoparticles in dentistry how far are we from clinical translation |
| topic | Inorganic nanoparticles Titanium dioxide Composite Antibacterial properties Mechanical properties Glossiness |
| url | http://www.sciencedirect.com/science/article/pii/S2405844025005493 |
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