From structure to therapy: the critical influence of cartilaginous endplates and microvascular network on intervertebral disc degeneration

The intervertebral disc (IVD) is the largest avascular structure in the human body. The cartilaginous endplate (CEP) is a layer of translucent cartilage located at the upper and lower edges of the vertebral bodies. On one hand, CEPs endure pressure from within the IVD and the tensile and shear force...

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Bibliographic Details
Main Authors: Yu Sun, Zhaoyong Li, Jiahao Duan, Enxu Liu, Lei Yang, Fei Sun, Long Chen, Shaofeng Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1489420/full
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