Screening of the Open Source Malaria Box Reveals an Early Lead Compound for the Treatment of Alveolar Echinococcosis.

The metacestode (larval) stage of the tapeworm Echinococcus multilocularis causes alveolar echinococcosis (AE), a very severe and in many cases incurable disease. To date, benzimidazoles such as albendazole and mebendazole are the only approved chemotherapeutical treatment options. Benzimidazoles in...

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Bibliographic Details
Main Authors: Britta Stadelmann, Reto Rufener, Denise Aeschbacher, Markus Spiliotis, Bruno Gottstein, Andrew Hemphill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0004535&type=printable
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