A comparison of 3 rheumatoid arthritis disease activity indices in routine clinical practice
Objective: The objective of this study was to appraise the correlation and agreement of RAPID 3 with DAS 28 and CDAI in terms of measuring disease activity/severity and for monitoring response to treatment at 2 and 4 month follow up. Methods: 105 adult literate persons having rheumatoid arthritis a...
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| Format: | Article |
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SAGE Publishing
2017-01-01
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| Series: | Indian Journal of Rheumatology |
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| Online Access: | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2017;volume=12;issue=4;spage=209;epage=213;aulast=Das |
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| author | Amit Kumar Das Rathindra Nath Sarkar Chandan Kumar Das Ritasman Baisya Urmimala Bhattacharjee Pallab Biswas Akashdip Bhattacharya |
| author_facet | Amit Kumar Das Rathindra Nath Sarkar Chandan Kumar Das Ritasman Baisya Urmimala Bhattacharjee Pallab Biswas Akashdip Bhattacharya |
| author_sort | Amit Kumar Das |
| collection | DOAJ |
| description | Objective: The objective of this study was to appraise the correlation and agreement of RAPID 3 with DAS 28 and CDAI in terms of measuring disease activity/severity and for monitoring response to treatment at 2 and 4 month follow up.
Methods: 105 adult literate persons having rheumatoid arthritis according to the 2010 ACR EULAR revised criteria were included. They were evaluated for disease activity by DAS 28, CDAI, and RAPID 3 scores. Response to treatment at 2 month and 4 month follow up was measured by these scores. Achievement of treatment target was defined as conversion from high/moderate disease activity at initial visit to low activity/remission at follow up visit.
Result: The mean DAS 28 (0-10), CDAI (0-76) , RAPID 3 (0-30) were 4.73 , 16.72, 10.72 respectively. There was substantial agreement between DAS 28 and RAPID 3 severity categories (kappa = 0.959, P < 0.0001) and also between CDAI and RAPID 3.
Conclusion: In a busy clinical setting, our study has shown usefulness of RAPID3 compared to the two most commonly used indices to assess disease activity in RA, both in terms of measuring quantitative disease activity as well as monitoring of treatment response at follow up visits. |
| format | Article |
| id | doaj-art-3614935c51ff4ff386de77f982278540 |
| institution | Kabale University |
| issn | 0973-3698 0973-3701 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Indian Journal of Rheumatology |
| spelling | doaj-art-3614935c51ff4ff386de77f9822785402025-02-03T12:00:34ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012017-01-0112420921310.4103/injr.injr_87_17A comparison of 3 rheumatoid arthritis disease activity indices in routine clinical practiceAmit Kumar DasRathindra Nath SarkarChandan Kumar DasRitasman BaisyaUrmimala BhattacharjeePallab BiswasAkashdip BhattacharyaObjective: The objective of this study was to appraise the correlation and agreement of RAPID 3 with DAS 28 and CDAI in terms of measuring disease activity/severity and for monitoring response to treatment at 2 and 4 month follow up. Methods: 105 adult literate persons having rheumatoid arthritis according to the 2010 ACR EULAR revised criteria were included. They were evaluated for disease activity by DAS 28, CDAI, and RAPID 3 scores. Response to treatment at 2 month and 4 month follow up was measured by these scores. Achievement of treatment target was defined as conversion from high/moderate disease activity at initial visit to low activity/remission at follow up visit. Result: The mean DAS 28 (0-10), CDAI (0-76) , RAPID 3 (0-30) were 4.73 , 16.72, 10.72 respectively. There was substantial agreement between DAS 28 and RAPID 3 severity categories (kappa = 0.959, P < 0.0001) and also between CDAI and RAPID 3. Conclusion: In a busy clinical setting, our study has shown usefulness of RAPID3 compared to the two most commonly used indices to assess disease activity in RA, both in terms of measuring quantitative disease activity as well as monitoring of treatment response at follow up visits.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2017;volume=12;issue=4;spage=209;epage=213;aulast=DasClinical Disease Activity Index ScoreDisease Activity Score 28rheumatoid arthritisroutine assessment of Patient Index Data 3 score |
| spellingShingle | Amit Kumar Das Rathindra Nath Sarkar Chandan Kumar Das Ritasman Baisya Urmimala Bhattacharjee Pallab Biswas Akashdip Bhattacharya A comparison of 3 rheumatoid arthritis disease activity indices in routine clinical practice Indian Journal of Rheumatology Clinical Disease Activity Index Score Disease Activity Score 28 rheumatoid arthritis routine assessment of Patient Index Data 3 score |
| title | A comparison of 3 rheumatoid arthritis disease activity indices in routine clinical practice |
| title_full | A comparison of 3 rheumatoid arthritis disease activity indices in routine clinical practice |
| title_fullStr | A comparison of 3 rheumatoid arthritis disease activity indices in routine clinical practice |
| title_full_unstemmed | A comparison of 3 rheumatoid arthritis disease activity indices in routine clinical practice |
| title_short | A comparison of 3 rheumatoid arthritis disease activity indices in routine clinical practice |
| title_sort | comparison of 3 rheumatoid arthritis disease activity indices in routine clinical practice |
| topic | Clinical Disease Activity Index Score Disease Activity Score 28 rheumatoid arthritis routine assessment of Patient Index Data 3 score |
| url | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2017;volume=12;issue=4;spage=209;epage=213;aulast=Das |
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