Efficacy of Plantago major Homoeopathic Mother Tincture as Mouth Wash in Comparison with Chlorhexidine Gluconate (0.2%) Mouthwash in Management of Oral Hygiene among Students: A Double-Blind, Parallel-group, Randomized Control Trial

Background: Plantago major (P. major) has anti-inflammatory, antimicrobial, and wound-healing properties. It also augments the production of nitric oxide which plays a role in protecting the gingival tissues against infection. Objective: The present study was carried out to assess and compare the ef...

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Main Authors: Kunal Deshmukh, Sahana Hegde Shetiya, Parth Aphale, Anindita Dutta, Dharmendra B. Sharma, Garvit Singh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Indian Association of Public Health Dentistry
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Online Access:https://journals.lww.com/10.4103/jiaphd.jiaphd_63_24
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author Kunal Deshmukh
Sahana Hegde Shetiya
Parth Aphale
Anindita Dutta
Dharmendra B. Sharma
Garvit Singh
author_facet Kunal Deshmukh
Sahana Hegde Shetiya
Parth Aphale
Anindita Dutta
Dharmendra B. Sharma
Garvit Singh
author_sort Kunal Deshmukh
collection DOAJ
description Background: Plantago major (P. major) has anti-inflammatory, antimicrobial, and wound-healing properties. It also augments the production of nitric oxide which plays a role in protecting the gingival tissues against infection. Objective: The present study was carried out to assess and compare the efficacy of P. major homeopathic mother tincture as mouthwash with 0.2% chlorhexidine gluconate (CHX) mouthwash for the treatment of gingivitis. Materials and Methods: A double-blind, randomized controlled parallel trial was conducted for 1 month. Sixty participants (15 males and 45 females) aged 18–22 years were randomly allocated into two groups by computer-generated random number; Group A: CHX gluconate 0.2% and Group B: P. major (mother tincture). Gingival index (GI) and plaque index (PI) were assessed by modified GI and Quigley-Hein PI at baseline and postintervention. Results: Mean rank and difference in GI and PI within the intervention group from baseline to 30 days were calculated using the Wilcoxon signed-rank test and paired t-test which was statistically significant (P < 0.001). However, there was no statistical significance between the P. major and CHX group postintervention for PI and GI. Conclusion: The double-blind trial conducted to confirm the anti-inflammatory properties of P. major mouthwash has shown efficacy in reducing both PI and GI from baseline to 30 days. However, there was no significant difference in GI and PI between the CHX mouthwash (0.2%) and P. major mouthwash group at the end of the trial.
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institution Kabale University
issn 2319-5932
2350-0484
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publisher Wolters Kluwer Medknow Publications
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series Journal of Indian Association of Public Health Dentistry
spelling doaj-art-360eedcb6c6541c29b4d01a60cb756ff2025-02-06T09:54:57ZengWolters Kluwer Medknow PublicationsJournal of Indian Association of Public Health Dentistry2319-59322350-04842024-12-0122432833310.4103/jiaphd.jiaphd_63_24Efficacy of Plantago major Homoeopathic Mother Tincture as Mouth Wash in Comparison with Chlorhexidine Gluconate (0.2%) Mouthwash in Management of Oral Hygiene among Students: A Double-Blind, Parallel-group, Randomized Control TrialKunal DeshmukhSahana Hegde ShetiyaParth AphaleAnindita DuttaDharmendra B. SharmaGarvit SinghBackground: Plantago major (P. major) has anti-inflammatory, antimicrobial, and wound-healing properties. It also augments the production of nitric oxide which plays a role in protecting the gingival tissues against infection. Objective: The present study was carried out to assess and compare the efficacy of P. major homeopathic mother tincture as mouthwash with 0.2% chlorhexidine gluconate (CHX) mouthwash for the treatment of gingivitis. Materials and Methods: A double-blind, randomized controlled parallel trial was conducted for 1 month. Sixty participants (15 males and 45 females) aged 18–22 years were randomly allocated into two groups by computer-generated random number; Group A: CHX gluconate 0.2% and Group B: P. major (mother tincture). Gingival index (GI) and plaque index (PI) were assessed by modified GI and Quigley-Hein PI at baseline and postintervention. Results: Mean rank and difference in GI and PI within the intervention group from baseline to 30 days were calculated using the Wilcoxon signed-rank test and paired t-test which was statistically significant (P < 0.001). However, there was no statistical significance between the P. major and CHX group postintervention for PI and GI. Conclusion: The double-blind trial conducted to confirm the anti-inflammatory properties of P. major mouthwash has shown efficacy in reducing both PI and GI from baseline to 30 days. However, there was no significant difference in GI and PI between the CHX mouthwash (0.2%) and P. major mouthwash group at the end of the trial.https://journals.lww.com/10.4103/jiaphd.jiaphd_63_24chlorhexidine gluconatedental plaque indicesgingivitisplantago
spellingShingle Kunal Deshmukh
Sahana Hegde Shetiya
Parth Aphale
Anindita Dutta
Dharmendra B. Sharma
Garvit Singh
Efficacy of Plantago major Homoeopathic Mother Tincture as Mouth Wash in Comparison with Chlorhexidine Gluconate (0.2%) Mouthwash in Management of Oral Hygiene among Students: A Double-Blind, Parallel-group, Randomized Control Trial
Journal of Indian Association of Public Health Dentistry
chlorhexidine gluconate
dental plaque indices
gingivitis
plantago
title Efficacy of Plantago major Homoeopathic Mother Tincture as Mouth Wash in Comparison with Chlorhexidine Gluconate (0.2%) Mouthwash in Management of Oral Hygiene among Students: A Double-Blind, Parallel-group, Randomized Control Trial
title_full Efficacy of Plantago major Homoeopathic Mother Tincture as Mouth Wash in Comparison with Chlorhexidine Gluconate (0.2%) Mouthwash in Management of Oral Hygiene among Students: A Double-Blind, Parallel-group, Randomized Control Trial
title_fullStr Efficacy of Plantago major Homoeopathic Mother Tincture as Mouth Wash in Comparison with Chlorhexidine Gluconate (0.2%) Mouthwash in Management of Oral Hygiene among Students: A Double-Blind, Parallel-group, Randomized Control Trial
title_full_unstemmed Efficacy of Plantago major Homoeopathic Mother Tincture as Mouth Wash in Comparison with Chlorhexidine Gluconate (0.2%) Mouthwash in Management of Oral Hygiene among Students: A Double-Blind, Parallel-group, Randomized Control Trial
title_short Efficacy of Plantago major Homoeopathic Mother Tincture as Mouth Wash in Comparison with Chlorhexidine Gluconate (0.2%) Mouthwash in Management of Oral Hygiene among Students: A Double-Blind, Parallel-group, Randomized Control Trial
title_sort efficacy of plantago major homoeopathic mother tincture as mouth wash in comparison with chlorhexidine gluconate 0 2 mouthwash in management of oral hygiene among students a double blind parallel group randomized control trial
topic chlorhexidine gluconate
dental plaque indices
gingivitis
plantago
url https://journals.lww.com/10.4103/jiaphd.jiaphd_63_24
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