Postmenopausal Deep Infiltrating Endometriosis of the Colon: Rare Location and Novel Medical Therapy

We report an uncommon case of deep infiltrating endometriosis of the colon presenting as iron deficiency anemia nine years after hysterectomy with bilateral salpingo-oophorectomy. The endometrial implant was found at the hepatic flexure, an exceedingly rare location for endometriosis invasion with n...

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Main Authors: Benjamin M. Snyder, Joseph W. Beets, Bruce A. Lessey, Samuel R. W. Horton, Gary A. Abrams
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2018/9587536
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author Benjamin M. Snyder
Joseph W. Beets
Bruce A. Lessey
Samuel R. W. Horton
Gary A. Abrams
author_facet Benjamin M. Snyder
Joseph W. Beets
Bruce A. Lessey
Samuel R. W. Horton
Gary A. Abrams
author_sort Benjamin M. Snyder
collection DOAJ
description We report an uncommon case of deep infiltrating endometriosis of the colon presenting as iron deficiency anemia nine years after hysterectomy with bilateral salpingo-oophorectomy. The endometrial implant was found at the hepatic flexure, an exceedingly rare location for endometriosis invasion with no cases distinctly reported in the literature. Additionally, the presentation of gastrointestinal endometriosis as iron deficiency anemia is not well documented in the literature. Instead of surgery, we prescribed a novel medical therapeutic approach using conjugated estrogen-bazedoxifene to antagonize the proliferative effects of estrogen on endometrial tissue. After five months of therapy and repeat colonoscopy, no evidence of endometrial tissue remained in the hepatic flexure.
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series Case Reports in Gastrointestinal Medicine
spelling doaj-art-360cd501a78c46098125a16bb18a0cff2025-02-03T05:51:44ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362018-01-01201810.1155/2018/95875369587536Postmenopausal Deep Infiltrating Endometriosis of the Colon: Rare Location and Novel Medical TherapyBenjamin M. Snyder0Joseph W. Beets1Bruce A. Lessey2Samuel R. W. Horton3Gary A. Abrams4University of South Carolina School of Medicine Greenville, Greenville, SC, USADepartment of Gastroenterology/Liver Center, Greenville Health System, University of South Carolina School of Medicine Greenville, Greenville, SC, USADepartment of Obstetrics and Gynecology, Greenville Health System, University of South Carolina School of Medicine Greenville, Greenville, SC, USADepartment of Pathology, Greenville Health System, University of South Carolina School of Medicine Greenville, Greenville, SC, USADepartment of Gastroenterology/Liver Center, Greenville Health System, University of South Carolina School of Medicine Greenville, Greenville, SC, USAWe report an uncommon case of deep infiltrating endometriosis of the colon presenting as iron deficiency anemia nine years after hysterectomy with bilateral salpingo-oophorectomy. The endometrial implant was found at the hepatic flexure, an exceedingly rare location for endometriosis invasion with no cases distinctly reported in the literature. Additionally, the presentation of gastrointestinal endometriosis as iron deficiency anemia is not well documented in the literature. Instead of surgery, we prescribed a novel medical therapeutic approach using conjugated estrogen-bazedoxifene to antagonize the proliferative effects of estrogen on endometrial tissue. After five months of therapy and repeat colonoscopy, no evidence of endometrial tissue remained in the hepatic flexure.http://dx.doi.org/10.1155/2018/9587536
spellingShingle Benjamin M. Snyder
Joseph W. Beets
Bruce A. Lessey
Samuel R. W. Horton
Gary A. Abrams
Postmenopausal Deep Infiltrating Endometriosis of the Colon: Rare Location and Novel Medical Therapy
Case Reports in Gastrointestinal Medicine
title Postmenopausal Deep Infiltrating Endometriosis of the Colon: Rare Location and Novel Medical Therapy
title_full Postmenopausal Deep Infiltrating Endometriosis of the Colon: Rare Location and Novel Medical Therapy
title_fullStr Postmenopausal Deep Infiltrating Endometriosis of the Colon: Rare Location and Novel Medical Therapy
title_full_unstemmed Postmenopausal Deep Infiltrating Endometriosis of the Colon: Rare Location and Novel Medical Therapy
title_short Postmenopausal Deep Infiltrating Endometriosis of the Colon: Rare Location and Novel Medical Therapy
title_sort postmenopausal deep infiltrating endometriosis of the colon rare location and novel medical therapy
url http://dx.doi.org/10.1155/2018/9587536
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