Programmatic mapping and size estimation of people who inject drugs to plan targeted HIV prevention and harm reduction programs in iran, a nationwide study

Abstract Background The HIV epidemic in Iran has been largely driven by people who inject drugs (PWID). Although harm reduction services have been implemented in Iran, some PWID still lack access to these services. This programmatic mapping aimed to determine the spatial distribution of hotspots, es...

Full description

Saved in:
Bibliographic Details
Main Authors: Nima Ghalekhani, Ahmad Hajebi, Ebrahim Ghodusi, Behnaz Beygi, Toktam Khojasteh Bojnordi, Mohammad Farooq Mashhour, Fatemeh Rezaei Sharif, Farzaneh Rajabzadeh, Hooriyeh Khoshdel, Hamid Reza Fathi, Hamid Sharifi
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Public Health
Subjects:
Online Access:https://doi.org/10.1186/s12889-025-23558-7
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849738316174327808
author Nima Ghalekhani
Ahmad Hajebi
Ebrahim Ghodusi
Behnaz Beygi
Toktam Khojasteh Bojnordi
Mohammad Farooq Mashhour
Fatemeh Rezaei Sharif
Farzaneh Rajabzadeh
Hooriyeh Khoshdel
Hamid Reza Fathi
Hamid Sharifi
author_facet Nima Ghalekhani
Ahmad Hajebi
Ebrahim Ghodusi
Behnaz Beygi
Toktam Khojasteh Bojnordi
Mohammad Farooq Mashhour
Fatemeh Rezaei Sharif
Farzaneh Rajabzadeh
Hooriyeh Khoshdel
Hamid Reza Fathi
Hamid Sharifi
author_sort Nima Ghalekhani
collection DOAJ
description Abstract Background The HIV epidemic in Iran has been largely driven by people who inject drugs (PWID). Although harm reduction services have been implemented in Iran, some PWID still lack access to these services. This programmatic mapping aimed to determine the spatial distribution of hotspots, estimate the number of PWID, and assess the coverage of prevention services to plan optimal service locations in Iran. Methods A cross-sectional key informant-driven mapping and enumeration methodology was used to identify hotspots of illicit drug use in 82 cities across 24 provinces in Iran from August 2020 to March 2021. Results We identified 4,270 active hotspots, of which 3,350 (78.5%) were associated with people who inject drugs (PWID). An estimated 14,737 PWID (92.2% male) were identified, with 261 (1.8%) under 18 years old, 3,643 (24.7%) aged 18–29 years, 10,061 (68.3%) aged 30–59 years, and 775 (5.2%) over 60 years old. Only half of the hotspots for PWID have active programs, with 24% of services overlapping in coverage areas. Under resource limitation with 47% and 93% reduction in the centers and outreach teams, respectively, we can expect just a 14% decline in services, and this would be the optimum decision in the constrained situation. Conclusions This study provides conclusive evidence that the current spatial distribution of harm reduction services for PWID in Iran is inefficient, characterized by significant coverage gaps in high-risk areas alongside costly resource redundancy through service overlap. Strategic consolidation based on spatial optimization can dramatically improve efficiency and access under resource constraints.
format Article
id doaj-art-35dfa4e2f5e14822b68f949eeac16f7a
institution DOAJ
issn 1471-2458
language English
publishDate 2025-07-01
publisher BMC
record_format Article
series BMC Public Health
spelling doaj-art-35dfa4e2f5e14822b68f949eeac16f7a2025-08-20T03:06:39ZengBMCBMC Public Health1471-24582025-07-0125111310.1186/s12889-025-23558-7Programmatic mapping and size estimation of people who inject drugs to plan targeted HIV prevention and harm reduction programs in iran, a nationwide studyNima Ghalekhani0Ahmad Hajebi1Ebrahim Ghodusi2Behnaz Beygi3Toktam Khojasteh Bojnordi4Mohammad Farooq Mashhour5Fatemeh Rezaei Sharif6Farzaneh Rajabzadeh7Hooriyeh Khoshdel8Hamid Reza Fathi9Hamid Sharifi10HIV/STI Surveillance Research Center, WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical SciencesResearch Center for Addiction and High-Risk Behaviors, Psychosocial Health Research Institute, Iran University of Medical SciencesMental Health, Social Health and Addiction Department (MEHSHAD), Ministry of Health and Medical Education (MOHME)Department of Environmental Health Engineering, Faculty of Health, Mashhad University of Medical ScienceMental Health, Social Health and Addiction Department (MEHSHAD), Ministry of Health and Medical Education (MOHME)Khorasan Razavi Management and Planning OrganizationDepartment of Biostatistics and Epidemiology, School of Public Health, Kerman University of Medical SciencesMinistry of Education and TrainingMental Health, Social Health and Addiction Department (MEHSHAD), Ministry of Health and Medical Education (MOHME)Department of Epidemiology and Biostatistics, School of Health, Mashhad University of Medical SciencesHIV/STI Surveillance Research Center, WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical SciencesAbstract Background The HIV epidemic in Iran has been largely driven by people who inject drugs (PWID). Although harm reduction services have been implemented in Iran, some PWID still lack access to these services. This programmatic mapping aimed to determine the spatial distribution of hotspots, estimate the number of PWID, and assess the coverage of prevention services to plan optimal service locations in Iran. Methods A cross-sectional key informant-driven mapping and enumeration methodology was used to identify hotspots of illicit drug use in 82 cities across 24 provinces in Iran from August 2020 to March 2021. Results We identified 4,270 active hotspots, of which 3,350 (78.5%) were associated with people who inject drugs (PWID). An estimated 14,737 PWID (92.2% male) were identified, with 261 (1.8%) under 18 years old, 3,643 (24.7%) aged 18–29 years, 10,061 (68.3%) aged 30–59 years, and 775 (5.2%) over 60 years old. Only half of the hotspots for PWID have active programs, with 24% of services overlapping in coverage areas. Under resource limitation with 47% and 93% reduction in the centers and outreach teams, respectively, we can expect just a 14% decline in services, and this would be the optimum decision in the constrained situation. Conclusions This study provides conclusive evidence that the current spatial distribution of harm reduction services for PWID in Iran is inefficient, characterized by significant coverage gaps in high-risk areas alongside costly resource redundancy through service overlap. Strategic consolidation based on spatial optimization can dramatically improve efficiency and access under resource constraints.https://doi.org/10.1186/s12889-025-23558-7People who inject drugsProgrammatic mappingPopulation size estimationHIVHarm reductionIran
spellingShingle Nima Ghalekhani
Ahmad Hajebi
Ebrahim Ghodusi
Behnaz Beygi
Toktam Khojasteh Bojnordi
Mohammad Farooq Mashhour
Fatemeh Rezaei Sharif
Farzaneh Rajabzadeh
Hooriyeh Khoshdel
Hamid Reza Fathi
Hamid Sharifi
Programmatic mapping and size estimation of people who inject drugs to plan targeted HIV prevention and harm reduction programs in iran, a nationwide study
BMC Public Health
People who inject drugs
Programmatic mapping
Population size estimation
HIV
Harm reduction
Iran
title Programmatic mapping and size estimation of people who inject drugs to plan targeted HIV prevention and harm reduction programs in iran, a nationwide study
title_full Programmatic mapping and size estimation of people who inject drugs to plan targeted HIV prevention and harm reduction programs in iran, a nationwide study
title_fullStr Programmatic mapping and size estimation of people who inject drugs to plan targeted HIV prevention and harm reduction programs in iran, a nationwide study
title_full_unstemmed Programmatic mapping and size estimation of people who inject drugs to plan targeted HIV prevention and harm reduction programs in iran, a nationwide study
title_short Programmatic mapping and size estimation of people who inject drugs to plan targeted HIV prevention and harm reduction programs in iran, a nationwide study
title_sort programmatic mapping and size estimation of people who inject drugs to plan targeted hiv prevention and harm reduction programs in iran a nationwide study
topic People who inject drugs
Programmatic mapping
Population size estimation
HIV
Harm reduction
Iran
url https://doi.org/10.1186/s12889-025-23558-7
work_keys_str_mv AT nimaghalekhani programmaticmappingandsizeestimationofpeoplewhoinjectdrugstoplantargetedhivpreventionandharmreductionprogramsinirananationwidestudy
AT ahmadhajebi programmaticmappingandsizeestimationofpeoplewhoinjectdrugstoplantargetedhivpreventionandharmreductionprogramsinirananationwidestudy
AT ebrahimghodusi programmaticmappingandsizeestimationofpeoplewhoinjectdrugstoplantargetedhivpreventionandharmreductionprogramsinirananationwidestudy
AT behnazbeygi programmaticmappingandsizeestimationofpeoplewhoinjectdrugstoplantargetedhivpreventionandharmreductionprogramsinirananationwidestudy
AT toktamkhojastehbojnordi programmaticmappingandsizeestimationofpeoplewhoinjectdrugstoplantargetedhivpreventionandharmreductionprogramsinirananationwidestudy
AT mohammadfarooqmashhour programmaticmappingandsizeestimationofpeoplewhoinjectdrugstoplantargetedhivpreventionandharmreductionprogramsinirananationwidestudy
AT fatemehrezaeisharif programmaticmappingandsizeestimationofpeoplewhoinjectdrugstoplantargetedhivpreventionandharmreductionprogramsinirananationwidestudy
AT farzanehrajabzadeh programmaticmappingandsizeestimationofpeoplewhoinjectdrugstoplantargetedhivpreventionandharmreductionprogramsinirananationwidestudy
AT hooriyehkhoshdel programmaticmappingandsizeestimationofpeoplewhoinjectdrugstoplantargetedhivpreventionandharmreductionprogramsinirananationwidestudy
AT hamidrezafathi programmaticmappingandsizeestimationofpeoplewhoinjectdrugstoplantargetedhivpreventionandharmreductionprogramsinirananationwidestudy
AT hamidsharifi programmaticmappingandsizeestimationofpeoplewhoinjectdrugstoplantargetedhivpreventionandharmreductionprogramsinirananationwidestudy