Severe Eosinophilic Meningoencephalitis Secondary to Suspected Neuroangiostrongyliasis with a Good Clinical Outcome

Angiostrongylus cantonensis has caused sporadic cases of eosinophilic meningoencephalitis in Sydney, Australia. We describe a 36-year-old man who presented subacutely with fevers, reduced level of consciousness, confusion, ophthalmoplegia, and urinary incontinence. He was diagnosed with severe eosin...

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Main Authors: Fabian Chiong, Andrew R. Lloyd, Jeffrey J. Post
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2019/4037196
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author Fabian Chiong
Andrew R. Lloyd
Jeffrey J. Post
author_facet Fabian Chiong
Andrew R. Lloyd
Jeffrey J. Post
author_sort Fabian Chiong
collection DOAJ
description Angiostrongylus cantonensis has caused sporadic cases of eosinophilic meningoencephalitis in Sydney, Australia. We describe a 36-year-old man who presented subacutely with fevers, reduced level of consciousness, confusion, ophthalmoplegia, and urinary incontinence. He was diagnosed with severe eosinophilic meningoencephalitis secondary to suspected Angiostrongylus cantonensis based on clinical, serological, and radiological findings. The patient was treated with albendazole and prednisolone with full neurological recovery. Management of neuroangiostrongyliasis with anthelminthic is controversial as it is thought to cause worsened outcomes through inciting an inflammatory response as a result of parasite killing. We managed to successfully treat our patient using albendazole and prednisolone and achieved a good outcome.
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series Case Reports in Infectious Diseases
spelling doaj-art-35ac55a2128a446bbb27059bcb98e2232025-02-03T07:25:51ZengWileyCase Reports in Infectious Diseases2090-66252090-66332019-01-01201910.1155/2019/40371964037196Severe Eosinophilic Meningoencephalitis Secondary to Suspected Neuroangiostrongyliasis with a Good Clinical OutcomeFabian Chiong0Andrew R. Lloyd1Jeffrey J. Post2Department of Infectious Diseases, Prince of Wales Hospital, Sydney, NSW, AustraliaDepartment of Infectious Diseases, Prince of Wales Hospital, Sydney, NSW, AustraliaDepartment of Infectious Diseases, Prince of Wales Hospital, Sydney, NSW, AustraliaAngiostrongylus cantonensis has caused sporadic cases of eosinophilic meningoencephalitis in Sydney, Australia. We describe a 36-year-old man who presented subacutely with fevers, reduced level of consciousness, confusion, ophthalmoplegia, and urinary incontinence. He was diagnosed with severe eosinophilic meningoencephalitis secondary to suspected Angiostrongylus cantonensis based on clinical, serological, and radiological findings. The patient was treated with albendazole and prednisolone with full neurological recovery. Management of neuroangiostrongyliasis with anthelminthic is controversial as it is thought to cause worsened outcomes through inciting an inflammatory response as a result of parasite killing. We managed to successfully treat our patient using albendazole and prednisolone and achieved a good outcome.http://dx.doi.org/10.1155/2019/4037196
spellingShingle Fabian Chiong
Andrew R. Lloyd
Jeffrey J. Post
Severe Eosinophilic Meningoencephalitis Secondary to Suspected Neuroangiostrongyliasis with a Good Clinical Outcome
Case Reports in Infectious Diseases
title Severe Eosinophilic Meningoencephalitis Secondary to Suspected Neuroangiostrongyliasis with a Good Clinical Outcome
title_full Severe Eosinophilic Meningoencephalitis Secondary to Suspected Neuroangiostrongyliasis with a Good Clinical Outcome
title_fullStr Severe Eosinophilic Meningoencephalitis Secondary to Suspected Neuroangiostrongyliasis with a Good Clinical Outcome
title_full_unstemmed Severe Eosinophilic Meningoencephalitis Secondary to Suspected Neuroangiostrongyliasis with a Good Clinical Outcome
title_short Severe Eosinophilic Meningoencephalitis Secondary to Suspected Neuroangiostrongyliasis with a Good Clinical Outcome
title_sort severe eosinophilic meningoencephalitis secondary to suspected neuroangiostrongyliasis with a good clinical outcome
url http://dx.doi.org/10.1155/2019/4037196
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