Anaesthesia and the Acute Phase Protein Response in Children Undergoing Circumcision
Concentrations of acute phase proteins (CRP: C-reactive protein, albumin) change during surgery. We investigated the acute phase response to circumcision and the effects of anaesthesia on this response. The children were divided into four groups; group 1 (intratracheal general anaesthesia, n=40), gr...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2005-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/MI.2005.312 |
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| _version_ | 1832556516754849792 |
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| author | Unase Buyukkocak Fatma Caglayan Osman Caglayan Murat Basar Murat Cakmak Ertan Batislam Sevgi Ulusoy |
| author_facet | Unase Buyukkocak Fatma Caglayan Osman Caglayan Murat Basar Murat Cakmak Ertan Batislam Sevgi Ulusoy |
| author_sort | Unase Buyukkocak |
| collection | DOAJ |
| description | Concentrations of acute phase proteins (CRP: C-reactive protein,
albumin) change during surgery. We investigated the acute phase
response to circumcision and the effects of anaesthesia on this
response. The children were divided into four groups; group 1
(intratracheal general anaesthesia, n=40), group 2 (general
anaesthesia with mask, n=20), group 3 (ketamine, n=20), group
4 (local anaesthesia, n=35). Blood samples were obtained, 24
hours before circumcision, after premedication, and 24 hours after
circumcision. CRP and albumin before circumcision were comparable
for all groups. There was no increase in CRP, and albumin remained
steady throughout the study. No difference was observed among the
groups, and related to anaesthesia. No responsiveness may be
explained with the size of injured tissue or anatomical and
histological type of preputium. |
| format | Article |
| id | doaj-art-35930bd3684b4bc6841a8ce6b7d7a568 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2005-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-35930bd3684b4bc6841a8ce6b7d7a5682025-02-03T05:45:10ZengWileyMediators of Inflammation0962-93511466-18612005-01-012005531231510.1155/MI.2005.312Anaesthesia and the Acute Phase Protein Response in Children Undergoing CircumcisionUnase Buyukkocak0Fatma Caglayan1Osman Caglayan2Murat Basar3Murat Cakmak4Ertan Batislam5Sevgi Ulusoy6Department of Anaesthesiology and Reanimation, School of Medicine, Kirikkale University, Kirikkale 71100, TurkeyDepartment of Pediatric Surgery, School of Medicine, Kirikkale University, Kirikkale 71100, TurkeyDepartment of Biochemistry, School of Medicine, Kirikkale University, Kirikkale 71100, TurkeyDepartment of Urology, School of Medicine, Kirikkale University, Kirikkale 71100, TurkeyDepartment of Pediatric Surgery, School of Medicine, Kirikkale University, Kirikkale 71100, TurkeyDepartment of Urology, School of Medicine, Kirikkale University, Kirikkale 71100, TurkeyDepartment of Pediatric Surgery, School of Medicine, Kirikkale University, Kirikkale 71100, TurkeyConcentrations of acute phase proteins (CRP: C-reactive protein, albumin) change during surgery. We investigated the acute phase response to circumcision and the effects of anaesthesia on this response. The children were divided into four groups; group 1 (intratracheal general anaesthesia, n=40), group 2 (general anaesthesia with mask, n=20), group 3 (ketamine, n=20), group 4 (local anaesthesia, n=35). Blood samples were obtained, 24 hours before circumcision, after premedication, and 24 hours after circumcision. CRP and albumin before circumcision were comparable for all groups. There was no increase in CRP, and albumin remained steady throughout the study. No difference was observed among the groups, and related to anaesthesia. No responsiveness may be explained with the size of injured tissue or anatomical and histological type of preputium.http://dx.doi.org/10.1155/MI.2005.312 |
| spellingShingle | Unase Buyukkocak Fatma Caglayan Osman Caglayan Murat Basar Murat Cakmak Ertan Batislam Sevgi Ulusoy Anaesthesia and the Acute Phase Protein Response in Children Undergoing Circumcision Mediators of Inflammation |
| title | Anaesthesia and the Acute Phase Protein Response in Children Undergoing Circumcision |
| title_full | Anaesthesia and the Acute Phase Protein Response in Children Undergoing Circumcision |
| title_fullStr | Anaesthesia and the Acute Phase Protein Response in Children Undergoing Circumcision |
| title_full_unstemmed | Anaesthesia and the Acute Phase Protein Response in Children Undergoing Circumcision |
| title_short | Anaesthesia and the Acute Phase Protein Response in Children Undergoing Circumcision |
| title_sort | anaesthesia and the acute phase protein response in children undergoing circumcision |
| url | http://dx.doi.org/10.1155/MI.2005.312 |
| work_keys_str_mv | AT unasebuyukkocak anaesthesiaandtheacutephaseproteinresponseinchildrenundergoingcircumcision AT fatmacaglayan anaesthesiaandtheacutephaseproteinresponseinchildrenundergoingcircumcision AT osmancaglayan anaesthesiaandtheacutephaseproteinresponseinchildrenundergoingcircumcision AT muratbasar anaesthesiaandtheacutephaseproteinresponseinchildrenundergoingcircumcision AT muratcakmak anaesthesiaandtheacutephaseproteinresponseinchildrenundergoingcircumcision AT ertanbatislam anaesthesiaandtheacutephaseproteinresponseinchildrenundergoingcircumcision AT sevgiulusoy anaesthesiaandtheacutephaseproteinresponseinchildrenundergoingcircumcision |