Functional effect of adiponectin and body composition assessment in lung cancer subjects after video‐assisted thoracoscopic surgery (VATS) lobectomy
Abstract Background Lung cancer is a pathology with an important incidence. It is a multifactorial disease characterized by epigenetic and nutritional factors. Indeed, there is a strong association between adipose tissue and the pulmonary system, and low‐grade inflammation of obese and/or overweight...
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Wiley
2025-01-01
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| Series: | Thoracic Cancer |
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| Online Access: | https://doi.org/10.1111/1759-7714.15260 |
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| author | Gaetana Messina Giovanni Natale Alfonso Fiorelli Maria Antonietta Puca Fiorenzo Moscatelli Vincenzo Monda Marcellino Monda Marina Di Domenico Carminia Maria Della Corte Gabriella Marsala Giuseppe Vicario Carmine Dalia Paola Bassi Beatrice Leonardi Antonella De Maria Antonietta Monda Giovanni Messina Antonietta Messina Rita Polito |
| author_facet | Gaetana Messina Giovanni Natale Alfonso Fiorelli Maria Antonietta Puca Fiorenzo Moscatelli Vincenzo Monda Marcellino Monda Marina Di Domenico Carminia Maria Della Corte Gabriella Marsala Giuseppe Vicario Carmine Dalia Paola Bassi Beatrice Leonardi Antonella De Maria Antonietta Monda Giovanni Messina Antonietta Messina Rita Polito |
| author_sort | Gaetana Messina |
| collection | DOAJ |
| description | Abstract Background Lung cancer is a pathology with an important incidence. It is a multifactorial disease characterized by epigenetic and nutritional factors. Indeed, there is a strong association between adipose tissue and the pulmonary system, and low‐grade inflammation of obese and/or overweight subjects have a pivotal role in lung cancer establishment. Methods In this study, we analyzed body composition through bioelectrical impedance analysis (BIA) and biochemical parameters such as glycemic and lipidic profile, inflammation profile and adiponectin serum levels in 30 patients (19 male; 11 women) undergoing video‐assisted thoracoscopic surgery (VATS) lobectomy for lung cancer from September 2021 to May 2022 at the Thoracic Unit of Luigi Vanvitelli University of Naples. A control group were also recruited (15 male; 15 female) consisting of age and sex matched volunteered subjects at the Thoracic Unit of Luigi Vanvitelli University of Naples. The control group and lung cancer patients were monitored for anthropometric and biochemical parameters before VATS lobectomy. Furthermore, the lung cancer patients were also monitored after 6 months of surgery. Results Body composition is modified after surgery and also albumin and C‐reactive protein (CRP) serum levels. In the overweight patients in our study, adiponectin levels were found to be reduced compared with the control group and increased in the same patients after VATS lobectomy. Conclusions Tumor removal as well as weight loss could affect adiponectin levels, and thus also a reduction in inflammation. In addition, weight loss could also be due to a psychological condition given by the intervention and not to malnutrition related to therapy. |
| format | Article |
| id | doaj-art-358620bc392e4081b983e365dbe9ef12 |
| institution | Kabale University |
| issn | 1759-7706 1759-7714 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Thoracic Cancer |
| spelling | doaj-art-358620bc392e4081b983e365dbe9ef122025-01-30T22:40:34ZengWileyThoracic Cancer1759-77061759-77142025-01-01162n/an/a10.1111/1759-7714.15260Functional effect of adiponectin and body composition assessment in lung cancer subjects after video‐assisted thoracoscopic surgery (VATS) lobectomyGaetana Messina0Giovanni Natale1Alfonso Fiorelli2Maria Antonietta Puca3Fiorenzo Moscatelli4Vincenzo Monda5Marcellino Monda6Marina Di Domenico7Carminia Maria Della Corte8Gabriella Marsala9Giuseppe Vicario10Carmine Dalia11Paola Bassi12Beatrice Leonardi13Antonella De Maria14Antonietta Monda15Giovanni Messina16Antonietta Messina17Rita Polito18Department of Translational Medicine Università degli Studi della Campania “Luigi Vanvitelli” Naples ItalyDepartment of Translational Medicine Università degli Studi della Campania “Luigi Vanvitelli” Naples ItalyDepartment of Translational Medicine Università degli Studi della Campania “Luigi Vanvitelli” Naples ItalyDepartment of Translational Medicine Università degli Studi della Campania “Luigi Vanvitelli” Naples ItalyDepartment of Human Sciences Telematic University Pegaso Naples ItalyDepartment of Economics, Law, Cybersecurity, and Sports Sciences University of Naples “Parthenope” Naples ItalyDepartment of Experimental Medicine Section of Human Physiology and Unit of Dietetics and Sports Medicine, University of Campania “Luigi Vanvitelli” Naples ItalyDepartment of Translational Medicine Università degli Studi della Campania “Luigi Vanvitelli” Naples ItalyDepartment of Translational Medicine Università degli Studi della Campania “Luigi Vanvitelli” Naples ItalyU.O.C. of Conventional Pharmaceuticals Catania ItalyDepartment of Translational Medicine Università degli Studi della Campania “Luigi Vanvitelli” Naples ItalyDepartment of Experimental Medicine University of Camapania “Luigi Vanvitelli” Naples ItalyDepartment of Experimental Medicine University of Camapania “Luigi Vanvitelli” Naples ItalyDepartment of Translational Medicine Università degli Studi della Campania “Luigi Vanvitelli” Naples ItalyDepartment of Human Sciences Telematic University Pegaso Naples ItalyDepartment of Human Sciences and Quality of Life Promotion Telematic University San Raffaele Rome ItalyDepartment of Experimental Medicine Section of Human Physiology and Unit of Dietetics and Sports Medicine, University of Campania “Luigi Vanvitelli” Naples ItalyDepartment of Precision Medicine University of Campania “Luigi Vanvitelli” Naples ItalyDepartment of Clinical and Experimental Medicine University of Foggia Foggia ItalyAbstract Background Lung cancer is a pathology with an important incidence. It is a multifactorial disease characterized by epigenetic and nutritional factors. Indeed, there is a strong association between adipose tissue and the pulmonary system, and low‐grade inflammation of obese and/or overweight subjects have a pivotal role in lung cancer establishment. Methods In this study, we analyzed body composition through bioelectrical impedance analysis (BIA) and biochemical parameters such as glycemic and lipidic profile, inflammation profile and adiponectin serum levels in 30 patients (19 male; 11 women) undergoing video‐assisted thoracoscopic surgery (VATS) lobectomy for lung cancer from September 2021 to May 2022 at the Thoracic Unit of Luigi Vanvitelli University of Naples. A control group were also recruited (15 male; 15 female) consisting of age and sex matched volunteered subjects at the Thoracic Unit of Luigi Vanvitelli University of Naples. The control group and lung cancer patients were monitored for anthropometric and biochemical parameters before VATS lobectomy. Furthermore, the lung cancer patients were also monitored after 6 months of surgery. Results Body composition is modified after surgery and also albumin and C‐reactive protein (CRP) serum levels. In the overweight patients in our study, adiponectin levels were found to be reduced compared with the control group and increased in the same patients after VATS lobectomy. Conclusions Tumor removal as well as weight loss could affect adiponectin levels, and thus also a reduction in inflammation. In addition, weight loss could also be due to a psychological condition given by the intervention and not to malnutrition related to therapy.https://doi.org/10.1111/1759-7714.15260body compositioninflammationlung cancernutritionvideo‐assisted thoracoscopic surgery (VATS) lobectomyweight loss |
| spellingShingle | Gaetana Messina Giovanni Natale Alfonso Fiorelli Maria Antonietta Puca Fiorenzo Moscatelli Vincenzo Monda Marcellino Monda Marina Di Domenico Carminia Maria Della Corte Gabriella Marsala Giuseppe Vicario Carmine Dalia Paola Bassi Beatrice Leonardi Antonella De Maria Antonietta Monda Giovanni Messina Antonietta Messina Rita Polito Functional effect of adiponectin and body composition assessment in lung cancer subjects after video‐assisted thoracoscopic surgery (VATS) lobectomy Thoracic Cancer body composition inflammation lung cancer nutrition video‐assisted thoracoscopic surgery (VATS) lobectomy weight loss |
| title | Functional effect of adiponectin and body composition assessment in lung cancer subjects after video‐assisted thoracoscopic surgery (VATS) lobectomy |
| title_full | Functional effect of adiponectin and body composition assessment in lung cancer subjects after video‐assisted thoracoscopic surgery (VATS) lobectomy |
| title_fullStr | Functional effect of adiponectin and body composition assessment in lung cancer subjects after video‐assisted thoracoscopic surgery (VATS) lobectomy |
| title_full_unstemmed | Functional effect of adiponectin and body composition assessment in lung cancer subjects after video‐assisted thoracoscopic surgery (VATS) lobectomy |
| title_short | Functional effect of adiponectin and body composition assessment in lung cancer subjects after video‐assisted thoracoscopic surgery (VATS) lobectomy |
| title_sort | functional effect of adiponectin and body composition assessment in lung cancer subjects after video assisted thoracoscopic surgery vats lobectomy |
| topic | body composition inflammation lung cancer nutrition video‐assisted thoracoscopic surgery (VATS) lobectomy weight loss |
| url | https://doi.org/10.1111/1759-7714.15260 |
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