Peroxisome Proliferator‐Activated Receptor (PPAR) Agonists for Patients With Primary Biliary Cholangitis With Inadequate Response to Ursodeoxycholic Acid (UDCA): A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Peroxisome Proliferator‐Activated Receptor (PPAR) Agonists for Patients With Primary Biliary Cholangitis With Inadequate Response to Ursodeoxycholic Acid (UDCA): A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

ABSTRACT Objective Peroxisome proliferator‐activated receptor (PPAR) agonists are agents used for patients with primary biliary cholangitis (PBC) who do not respond to conventional agents like ursodeoxycholic acid (UDCA). This meta‐analysis aimed to assess the safety and efficacy of PPAR agonists, i...

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Main Authors: Maadeha H. Zaidi, Zaroon Haider, FNU Sadia, Muhammad Tayyab, Muhammad Naveed Tariq, Hasaan H. Ans, Muhammad Bilal Javaid, Ahmad Khan, Muhammad Hassan Ahmad, Rahman Rasheed, Uzair Jafar, Huzaifa Ahmad Cheema, Asma'a Munasar Ali Alsubari, Muhammad Shahzil, Essam Rashad, Rehmat Ullah Awan, Hassam Ali, Prasun K. Jalal
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:JGH Open
Subjects:
elafibranor
fibrates
PBC
PPAR agonist
primary biliary cholangitis
saroglitazar
Online Access:https://doi.org/10.1002/jgh3.70196
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