Enhanced targeted treatment of cervical cancer using nanoparticle-based doxycycline delivery system

Enhanced targeted treatment of cervical cancer using nanoparticle-based doxycycline delivery system

Abstract This study investigates a nanoparticle-based doxycycline (DOX) delivery system targeting cervical cancer cells via the CD44 receptor. Molecular docking revealed a strong binding affinity between hyaluronic acid (HA) and CD44 (binding energy: -7.2 kJ/mol). Characterization of the HA-Chitosan...

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Bibliographic Details
Main Authors: Sadia Anjum, Ayesha Akhtar, Saleh M. Aldaqal, Maisa S. Abduh, Hammad Ahmad, Riaz Mustafa, Faiza Naseer, Maryam Sadia, Tahir Ahmad
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Doxycycline
Cervical Cancer
Novel Drug Delivery System
Sustained release
Targeted therapy
Immunotherapy
Online Access:https://doi.org/10.1038/s41598-024-84203-8
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