Pyoderma Gangrenosum and Autoimmune Chronic Active Hepatitis in a 17-Year-Old Female

A 17-year-old girl presented with fever, icterus and painful small nodules on her face and a larger nodular lesion on the left shin. The patient had fatigue, intermittent jaundice and abdominal pain over the preceding three months. The nodular lesions ulcerated and had the typical clinical and histo...

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Main Authors: Joanne M. Langley, Eve A. Roberts, Moshe Ipp, Ronald M. Laxer, Lionel Boxall, M. James Phillips
Format: Article
Language:English
Published: Wiley 1988-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1988/108457
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author Joanne M. Langley
Eve A. Roberts
Moshe Ipp
Ronald M. Laxer
Lionel Boxall
M. James Phillips
author_facet Joanne M. Langley
Eve A. Roberts
Moshe Ipp
Ronald M. Laxer
Lionel Boxall
M. James Phillips
author_sort Joanne M. Langley
collection DOAJ
description A 17-year-old girl presented with fever, icterus and painful small nodules on her face and a larger nodular lesion on the left shin. The patient had fatigue, intermittent jaundice and abdominal pain over the preceding three months. The nodular lesions ulcerated and had the typical clinical and histopathological appearance of pyoderma gangrenosum. Although there was no hepatosplenomegaly, serum aminotransferases and immunoglobulin G were elevated; antismooth muscle antibodies were detectable. Inflammatory bowel disease was not presenr. Autoimmune chronic active hepatitis and pyoderma gangrenosum are a rare association and this is the youngest patient in whom the association has been reported.
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institution Kabale University
issn 0835-7900
language English
publishDate 1988-01-01
publisher Wiley
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series Canadian Journal of Gastroenterology
spelling doaj-art-356e26cc0c474818b4798882dd2fdb7f2025-02-03T06:44:50ZengWileyCanadian Journal of Gastroenterology0835-79001988-01-012413713910.1155/1988/108457Pyoderma Gangrenosum and Autoimmune Chronic Active Hepatitis in a 17-Year-Old FemaleJoanne M. Langley0Eve A. Roberts1Moshe Ipp2Ronald M. Laxer3Lionel Boxall4M. James Phillips5Departments of Pediatrics and Pathology, The Hospital for Sick Children, Toronto, Ontario, CanadaDepartments of Pediatrics and Pathology, The Hospital for Sick Children, Toronto, Ontario, CanadaDepartments of Pediatrics and Pathology, The Hospital for Sick Children, Toronto, Ontario, CanadaDepartments of Pediatrics and Pathology, The Hospital for Sick Children, Toronto, Ontario, CanadaDepartments of Pediatrics and Pathology, The Hospital for Sick Children, Toronto, Ontario, CanadaDepartments of Pediatrics and Pathology, The Hospital for Sick Children, Toronto, Ontario, CanadaA 17-year-old girl presented with fever, icterus and painful small nodules on her face and a larger nodular lesion on the left shin. The patient had fatigue, intermittent jaundice and abdominal pain over the preceding three months. The nodular lesions ulcerated and had the typical clinical and histopathological appearance of pyoderma gangrenosum. Although there was no hepatosplenomegaly, serum aminotransferases and immunoglobulin G were elevated; antismooth muscle antibodies were detectable. Inflammatory bowel disease was not presenr. Autoimmune chronic active hepatitis and pyoderma gangrenosum are a rare association and this is the youngest patient in whom the association has been reported.http://dx.doi.org/10.1155/1988/108457
spellingShingle Joanne M. Langley
Eve A. Roberts
Moshe Ipp
Ronald M. Laxer
Lionel Boxall
M. James Phillips
Pyoderma Gangrenosum and Autoimmune Chronic Active Hepatitis in a 17-Year-Old Female
Canadian Journal of Gastroenterology
title Pyoderma Gangrenosum and Autoimmune Chronic Active Hepatitis in a 17-Year-Old Female
title_full Pyoderma Gangrenosum and Autoimmune Chronic Active Hepatitis in a 17-Year-Old Female
title_fullStr Pyoderma Gangrenosum and Autoimmune Chronic Active Hepatitis in a 17-Year-Old Female
title_full_unstemmed Pyoderma Gangrenosum and Autoimmune Chronic Active Hepatitis in a 17-Year-Old Female
title_short Pyoderma Gangrenosum and Autoimmune Chronic Active Hepatitis in a 17-Year-Old Female
title_sort pyoderma gangrenosum and autoimmune chronic active hepatitis in a 17 year old female
url http://dx.doi.org/10.1155/1988/108457
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AT mosheipp pyodermagangrenosumandautoimmunechronicactivehepatitisina17yearoldfemale
AT ronaldmlaxer pyodermagangrenosumandautoimmunechronicactivehepatitisina17yearoldfemale
AT lionelboxall pyodermagangrenosumandautoimmunechronicactivehepatitisina17yearoldfemale
AT mjamesphillips pyodermagangrenosumandautoimmunechronicactivehepatitisina17yearoldfemale