Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
Decitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia. We present a case of cardiomyopathy associated with decitabine used for secondary acute myelogenous leukemia. The patient pre...
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Format: | Article |
Language: | English |
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Wiley
2018-01-01
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Series: | Case Reports in Cardiology |
Online Access: | http://dx.doi.org/10.1155/2018/3953579 |
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author | Pradyumna Agasthi Hemalatha Narayanasamy Dan Sorajja James Slack Farouk Mookadam |
author_facet | Pradyumna Agasthi Hemalatha Narayanasamy Dan Sorajja James Slack Farouk Mookadam |
author_sort | Pradyumna Agasthi |
collection | DOAJ |
description | Decitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia. We present a case of cardiomyopathy associated with decitabine used for secondary acute myelogenous leukemia. The patient presented with new heart failure symptoms and an ejection fraction decline. |
format | Article |
id | doaj-art-3550fcc6a6154e098ee7a4d7637069e6 |
institution | Kabale University |
issn | 2090-6404 2090-6412 |
language | English |
publishDate | 2018-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Cardiology |
spelling | doaj-art-3550fcc6a6154e098ee7a4d7637069e62025-02-03T07:25:58ZengWileyCase Reports in Cardiology2090-64042090-64122018-01-01201810.1155/2018/39535793953579Decitabine Induced Delayed Cardiomyopathy in Hematologic MalignancyPradyumna Agasthi0Hemalatha Narayanasamy1Dan Sorajja2James Slack3Farouk Mookadam4Department of Cardiovascular Diseases, Mayo Clinic, Arizona 85259, USADepartment of Cardiovascular Diseases, Mayo Clinic, Arizona 85259, USADepartment of Cardiovascular Diseases, Mayo Clinic, Arizona 85259, USADepartment of Cardio-Oncology, Mayo Clinic, Arizona 85259, USADepartment of Cardiovascular Diseases, Mayo Clinic, Arizona 85259, USADecitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia. We present a case of cardiomyopathy associated with decitabine used for secondary acute myelogenous leukemia. The patient presented with new heart failure symptoms and an ejection fraction decline.http://dx.doi.org/10.1155/2018/3953579 |
spellingShingle | Pradyumna Agasthi Hemalatha Narayanasamy Dan Sorajja James Slack Farouk Mookadam Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy Case Reports in Cardiology |
title | Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy |
title_full | Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy |
title_fullStr | Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy |
title_full_unstemmed | Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy |
title_short | Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy |
title_sort | decitabine induced delayed cardiomyopathy in hematologic malignancy |
url | http://dx.doi.org/10.1155/2018/3953579 |
work_keys_str_mv | AT pradyumnaagasthi decitabineinduceddelayedcardiomyopathyinhematologicmalignancy AT hemalathanarayanasamy decitabineinduceddelayedcardiomyopathyinhematologicmalignancy AT dansorajja decitabineinduceddelayedcardiomyopathyinhematologicmalignancy AT jamesslack decitabineinduceddelayedcardiomyopathyinhematologicmalignancy AT faroukmookadam decitabineinduceddelayedcardiomyopathyinhematologicmalignancy |