Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy

Decitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia. We present a case of cardiomyopathy associated with decitabine used for secondary acute myelogenous leukemia. The patient pre...

Full description

Saved in:
Bibliographic Details
Main Authors: Pradyumna Agasthi, Hemalatha Narayanasamy, Dan Sorajja, James Slack, Farouk Mookadam
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2018/3953579
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832545358300839936
author Pradyumna Agasthi
Hemalatha Narayanasamy
Dan Sorajja
James Slack
Farouk Mookadam
author_facet Pradyumna Agasthi
Hemalatha Narayanasamy
Dan Sorajja
James Slack
Farouk Mookadam
author_sort Pradyumna Agasthi
collection DOAJ
description Decitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia. We present a case of cardiomyopathy associated with decitabine used for secondary acute myelogenous leukemia. The patient presented with new heart failure symptoms and an ejection fraction decline.
format Article
id doaj-art-3550fcc6a6154e098ee7a4d7637069e6
institution Kabale University
issn 2090-6404
2090-6412
language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Case Reports in Cardiology
spelling doaj-art-3550fcc6a6154e098ee7a4d7637069e62025-02-03T07:25:58ZengWileyCase Reports in Cardiology2090-64042090-64122018-01-01201810.1155/2018/39535793953579Decitabine Induced Delayed Cardiomyopathy in Hematologic MalignancyPradyumna Agasthi0Hemalatha Narayanasamy1Dan Sorajja2James Slack3Farouk Mookadam4Department of Cardiovascular Diseases, Mayo Clinic, Arizona 85259, USADepartment of Cardiovascular Diseases, Mayo Clinic, Arizona 85259, USADepartment of Cardiovascular Diseases, Mayo Clinic, Arizona 85259, USADepartment of Cardio-Oncology, Mayo Clinic, Arizona 85259, USADepartment of Cardiovascular Diseases, Mayo Clinic, Arizona 85259, USADecitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia. We present a case of cardiomyopathy associated with decitabine used for secondary acute myelogenous leukemia. The patient presented with new heart failure symptoms and an ejection fraction decline.http://dx.doi.org/10.1155/2018/3953579
spellingShingle Pradyumna Agasthi
Hemalatha Narayanasamy
Dan Sorajja
James Slack
Farouk Mookadam
Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
Case Reports in Cardiology
title Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
title_full Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
title_fullStr Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
title_full_unstemmed Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
title_short Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
title_sort decitabine induced delayed cardiomyopathy in hematologic malignancy
url http://dx.doi.org/10.1155/2018/3953579
work_keys_str_mv AT pradyumnaagasthi decitabineinduceddelayedcardiomyopathyinhematologicmalignancy
AT hemalathanarayanasamy decitabineinduceddelayedcardiomyopathyinhematologicmalignancy
AT dansorajja decitabineinduceddelayedcardiomyopathyinhematologicmalignancy
AT jamesslack decitabineinduceddelayedcardiomyopathyinhematologicmalignancy
AT faroukmookadam decitabineinduceddelayedcardiomyopathyinhematologicmalignancy