A Review of Psoriasis, a Known Risk Factor for Cardiovascular Disease and Its Impact on Folate and Homocysteine Metabolism
Psoriasis is a chronic inflammatory skin condition with an increased risk of cardiovascular disease. This risk has been attributed to an association with many independent risk factors including obesity, hypertension, smoking, and dyslipidemia. Psoriasis patients also have lower levels of folate and...
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Format: | Article |
Language: | English |
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Wiley
2012-01-01
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Series: | Journal of Nutrition and Metabolism |
Online Access: | http://dx.doi.org/10.1155/2012/965385 |
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author | Ian McDonald Maureen Connolly Anne-Marie Tobin |
author_facet | Ian McDonald Maureen Connolly Anne-Marie Tobin |
author_sort | Ian McDonald |
collection | DOAJ |
description | Psoriasis is a chronic inflammatory skin condition with an increased risk of cardiovascular disease. This risk has been attributed to an association with many independent risk factors including obesity, hypertension, smoking, and dyslipidemia. Psoriasis patients also have lower levels of folate and conversely higher levels of homocysteine, which in itself is a risk factor for cardiovascular disease. It has been postulated that low folate levels in this group may be a direct cause of hyperhomocysteinemia and therefore a treatable risk factor by folate supplementation. This paper looks at the literature published to date on the relationship between psoriasis, homocysteine, and folate levels. |
format | Article |
id | doaj-art-354c25c3f28b4a36ae899aeb2746dcc1 |
institution | Kabale University |
issn | 2090-0724 2090-0732 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | Journal of Nutrition and Metabolism |
spelling | doaj-art-354c25c3f28b4a36ae899aeb2746dcc12025-02-03T01:32:39ZengWileyJournal of Nutrition and Metabolism2090-07242090-07322012-01-01201210.1155/2012/965385965385A Review of Psoriasis, a Known Risk Factor for Cardiovascular Disease and Its Impact on Folate and Homocysteine MetabolismIan McDonald0Maureen Connolly1Anne-Marie Tobin2Department of Dermatology, The Adelaide and Meath Hospital Incorporating the National Children’s Hospital, Tallaght, Dublin 24, IrelandDepartment of Dermatology, The Adelaide and Meath Hospital Incorporating the National Children’s Hospital, Tallaght, Dublin 24, IrelandDepartment of Dermatology, The Adelaide and Meath Hospital Incorporating the National Children’s Hospital, Tallaght, Dublin 24, IrelandPsoriasis is a chronic inflammatory skin condition with an increased risk of cardiovascular disease. This risk has been attributed to an association with many independent risk factors including obesity, hypertension, smoking, and dyslipidemia. Psoriasis patients also have lower levels of folate and conversely higher levels of homocysteine, which in itself is a risk factor for cardiovascular disease. It has been postulated that low folate levels in this group may be a direct cause of hyperhomocysteinemia and therefore a treatable risk factor by folate supplementation. This paper looks at the literature published to date on the relationship between psoriasis, homocysteine, and folate levels.http://dx.doi.org/10.1155/2012/965385 |
spellingShingle | Ian McDonald Maureen Connolly Anne-Marie Tobin A Review of Psoriasis, a Known Risk Factor for Cardiovascular Disease and Its Impact on Folate and Homocysteine Metabolism Journal of Nutrition and Metabolism |
title | A Review of Psoriasis, a Known Risk Factor for Cardiovascular Disease and Its Impact on Folate and Homocysteine Metabolism |
title_full | A Review of Psoriasis, a Known Risk Factor for Cardiovascular Disease and Its Impact on Folate and Homocysteine Metabolism |
title_fullStr | A Review of Psoriasis, a Known Risk Factor for Cardiovascular Disease and Its Impact on Folate and Homocysteine Metabolism |
title_full_unstemmed | A Review of Psoriasis, a Known Risk Factor for Cardiovascular Disease and Its Impact on Folate and Homocysteine Metabolism |
title_short | A Review of Psoriasis, a Known Risk Factor for Cardiovascular Disease and Its Impact on Folate and Homocysteine Metabolism |
title_sort | review of psoriasis a known risk factor for cardiovascular disease and its impact on folate and homocysteine metabolism |
url | http://dx.doi.org/10.1155/2012/965385 |
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