Ileocecal Intussusception with Histomorphological Features of Inflammatory Neuropathy in Adenovirus Infection

The pathophysiological mechanisms for ileocecal intussusception in children with adenovirus infection are not well characterized. Here we demonstrate coincidence of adenovirus infection and inflammatory neuropathy of myenteric plexus in two children with ileocecal intussusception. Inflammatory neuro...

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Main Authors: Elke Kaemmerer, Jens J. W. Tischendorf, Gerd Steinau, Norbert Wagner, Nikolaus Gassler
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2009/579501
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author Elke Kaemmerer
Jens J. W. Tischendorf
Gerd Steinau
Norbert Wagner
Nikolaus Gassler
author_facet Elke Kaemmerer
Jens J. W. Tischendorf
Gerd Steinau
Norbert Wagner
Nikolaus Gassler
author_sort Elke Kaemmerer
collection DOAJ
description The pathophysiological mechanisms for ileocecal intussusception in children with adenovirus infection are not well characterized. Here we demonstrate coincidence of adenovirus infection and inflammatory neuropathy of myenteric plexus in two children with ileocecal intussusception. Inflammatory neuropathy, an unspecific morphological feature which is found in peristalsis disorders, was morphologically characterized by the influx of CD3 positive lymphocytes in nervous plexus. To our knowledge, this is the first report suggesting peristalsis disorders from inflammatory neuropathy as additional mechanism in the pathophysiological concept of adenovirus-associated ileocecal intussusception.
format Article
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institution Kabale University
issn 1687-6121
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language English
publishDate 2009-01-01
publisher Wiley
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series Gastroenterology Research and Practice
spelling doaj-art-3528954acbd74e238c5ae5c45e3e70522025-02-03T05:45:36ZengWileyGastroenterology Research and Practice1687-61211687-630X2009-01-01200910.1155/2009/579501579501Ileocecal Intussusception with Histomorphological Features of Inflammatory Neuropathy in Adenovirus InfectionElke Kaemmerer0Jens J. W. Tischendorf1Gerd Steinau2Norbert Wagner3Nikolaus Gassler4Department of Pediatrics, RWTH Aachen University, 52074 Aachen, GermanyDepartment of Medicine III, RWTH Aachen University, 52074 Aachen, GermanyDepartment of Surgery, RWTH Aachen University, 52074 Aachen, GermanyDepartment of Pediatrics, RWTH Aachen University, 52074 Aachen, GermanyInstitute of Pathology, RWTH Aachen University, 52074 Aachen, GermanyThe pathophysiological mechanisms for ileocecal intussusception in children with adenovirus infection are not well characterized. Here we demonstrate coincidence of adenovirus infection and inflammatory neuropathy of myenteric plexus in two children with ileocecal intussusception. Inflammatory neuropathy, an unspecific morphological feature which is found in peristalsis disorders, was morphologically characterized by the influx of CD3 positive lymphocytes in nervous plexus. To our knowledge, this is the first report suggesting peristalsis disorders from inflammatory neuropathy as additional mechanism in the pathophysiological concept of adenovirus-associated ileocecal intussusception.http://dx.doi.org/10.1155/2009/579501
spellingShingle Elke Kaemmerer
Jens J. W. Tischendorf
Gerd Steinau
Norbert Wagner
Nikolaus Gassler
Ileocecal Intussusception with Histomorphological Features of Inflammatory Neuropathy in Adenovirus Infection
Gastroenterology Research and Practice
title Ileocecal Intussusception with Histomorphological Features of Inflammatory Neuropathy in Adenovirus Infection
title_full Ileocecal Intussusception with Histomorphological Features of Inflammatory Neuropathy in Adenovirus Infection
title_fullStr Ileocecal Intussusception with Histomorphological Features of Inflammatory Neuropathy in Adenovirus Infection
title_full_unstemmed Ileocecal Intussusception with Histomorphological Features of Inflammatory Neuropathy in Adenovirus Infection
title_short Ileocecal Intussusception with Histomorphological Features of Inflammatory Neuropathy in Adenovirus Infection
title_sort ileocecal intussusception with histomorphological features of inflammatory neuropathy in adenovirus infection
url http://dx.doi.org/10.1155/2009/579501
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AT gerdsteinau ileocecalintussusceptionwithhistomorphologicalfeaturesofinflammatoryneuropathyinadenovirusinfection
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